Neurodegenerative diseases are increasing in number, given that the general global
population is becoming older. They manifest themselves through mechanisms that are not …

Temporal lobe epilepsy (TLE) is frequently associated with hippocampal sclerosis, possibly
caused by a primary brain injury that occurred a long time before the appearance of …

Among the severe side effects induced by cisplatin chemotherapy, muscle wasting is the
most relevant one. This effect is a major cause for a clinical decline of cancer patients, since …

Various ketogenic diet (KD) therapies, including classic KD, medium chain triglyceride
administration, low glycemic index treatment, and a modified Atkins diet, have been …

Nerve agents and some pesticides such as diisopropylfluorophosphate (DFP) cause
neurotoxic manifestations that include seizures and status epilepticus (SE), which are …

The gut hormone ghrelin is widely beneficial in many disease states. However, ghrelin exists
in two distinctive isoforms, each with its own metabolic profile. In Parkinson's Disease (PD) …

Hericium erinaceus (HE), a culinary-medicinal mushroom, has shown therapeutic potential
in many brain diseases. However, the role of HE in status epilepticus (SE)-mediated …

Ghrelin, des-acyl ghrelin and other related peptides possess anticonvulsant activities.
Although ghrelin and cognate peptides were shown to physiologically regulate only the …

The ketogenic diet (KD) is a high-fat, low carbohydrate nutritional treatment adopted in
several countries for refractory epilepsy. However, the use of KD is limited by adverse events …

Rhynchophylline (RIN) is a significant active component isolated from the Chinese herbal
medicine Uncaria rhynchophylla. Several studies have demonstrated that RIN has a …