Diversity and dynamism in the cerebellum

CI De Zeeuw, SG Lisberger, JL Raymond - Nature neuroscience, 2021 - nature.com
The past several years have brought revelations and paradigm shifts in research on the
cerebellum. Historically viewed as a simple sensorimotor controller with homogeneous …

Bidirectional learning in upbound and downbound microzones of the cerebellum

CI De Zeeuw - Nature Reviews Neuroscience, 2021 - nature.com
Over the past several decades, theories about cerebellar learning have evolved. A relatively
simple view that highlighted the contribution of one major form of heterosynaptic plasticity to …

Intrinsic plasticity of cerebellar purkinje cells contributes to motor memory consolidation

DC Jang, HG Shim, SJ Kim - Journal of Neuroscience, 2020 - jneurosci.org
Intrinsic plasticity of cerebellar Purkinje cells (PCs) has recently been demonstrated in
cerebellar local circuits; however, its physiological impact on cerebellar learning and …

New advances regarding adaptation of the vestibulo-ocular reflex

MC Schubert, AA Migliaccio - Journal of neurophysiology, 2019 - journals.physiology.org
This is a review summarizing the development of vestibulo-ocular reflex (VOR) adaptation
behavior with relevance to rehabilitation over the last 10 years and examines VOR …

[HTML][HTML] The effect of expertise during simulated flight emergencies on the autonomic response and operative performance in military pilots

S Santos, JA Parraca, O Fernandes… - International Journal of …, 2022 - mdpi.com
Heart rate variability (HRV) and performance response during emergency flight maneuvers
were analyzed. Two expert pilots (ages 35 and 33) and two rookie pilots (ages 25) from the …

Surgical techniques and functional evaluation for vestibular lesions in the mouse: unilateral labyrinthectomy (UL) and unilateral vestibular neurectomy (UVN)

F Simon, D Pericat, C Djian, D Fricker, F Denoyelle… - Journal of …, 2020 - Springer
Objective Unilateral labyrinthectomy (UL) and unilateral vestibular neurectomy (UVN) are
two surgical methods to produce vestibular lesions in the mouse. The objective of this study …

Extended time frame for restoring inner ear function through gene therapy in Usher1G preclinical model

G Lahlou, C Calvet, F Simon, V Michel, L Alciato… - JCI …, 2024 - pmc.ncbi.nlm.nih.gov
Neonatal gene therapy has been shown to prevent inner ear dysfunction in mouse models
of Usher syndrome type I (USH1), the most common genetic cause of combined deafness …

[HTML][HTML] Behind mouse eyes: The function and control of eye movements in mice

EA Giovannetti, E Rancz - Neuroscience & Biobehavioral Reviews, 2024 - Elsevier
The mouse visual system has become the most popular model to study the cellular and
circuit mechanisms of sensory processing. However, the importance of eye movements only …

Morphological and functional correlates of vestibular synaptic deafferentation and repair in a mouse model of acute-onset vertigo

R Cassel, P Bordiga, J Carcaud… - Disease Models & …, 2019 - journals.biologists.com
Damage to cochlear primary afferent synapses has been shown to be a key factor in various
auditory pathologies. Similarly, the selective lesioning of primary vestibular synapses might …

Human vestibulo-ocular reflex adaptation training: time beats quantity

M Muntaseer Mahfuz, MC Schubert… - Journal of the …, 2018 - Springer
The vestibulo-ocular reflex (VOR) is the main gaze stabilising system during rapid head
movements. The VOR is highly plastic and its gain (eye/head velocity) can be increased via …