Functional connectivity of amygdala subnuclei in PTSD: a narrative review
While the amygdala is often implicated in the neurobiology of posttraumatic stress disorder
(PTSD), the pattern of results remains mixed. One reason for this may be the heterogeneity …
(PTSD), the pattern of results remains mixed. One reason for this may be the heterogeneity …
Early-life inflammation promotes depressive symptoms in adolescence via microglial engulfment of dendritic spines
P Cao, C Chen, A Liu, Q Shan, X Zhu, C Jia, X Peng… - Neuron, 2021 - cell.com
Early-life inflammation increases the risk for depression in later life. Here, we demonstrate
how early-life inflammation causes adolescent depressive-like symptoms: by altering the …
how early-life inflammation causes adolescent depressive-like symptoms: by altering the …
Understanding the dynamic and destiny of memories
Memory formation enables the retention of life experiences overtime. Based on previously
acquired information, organisms can anticipate future events and adjust their behaviors to …
acquired information, organisms can anticipate future events and adjust their behaviors to …
Genetically identified amygdala–striatal circuits for valence-specific behaviors
The basolateral amygdala (BLA) plays essential roles in behaviors motivated by stimuli with
either positive or negative valence, but how it processes motivationally opposing information …
either positive or negative valence, but how it processes motivationally opposing information …
Estimation of current and future physiological states in insular cortex
Interoception, the sense of internal bodily signals, is essential for physiological homeostasis,
cognition, and emotions. While human insular cortex (InsCtx) is implicated in interoception …
cognition, and emotions. While human insular cortex (InsCtx) is implicated in interoception …
[HTML][HTML] Amygdala reward neurons form and store fear extinction memory
The ability to extinguish conditioned fear memory is critical for adaptive control of fear
response, and its impairment is a hallmark of emotional disorders like post-traumatic stress …
response, and its impairment is a hallmark of emotional disorders like post-traumatic stress …
Prefrontal circuits encode both general danger and specific threat representations
Behavioral adaptation to potential threats requires both a global representation of danger to
prepare the organism to react in a timely manner but also the identification of specific …
prepare the organism to react in a timely manner but also the identification of specific …
Fear extinction relies on ventral hippocampal safety codes shaped by the amygdala
Extinction memory retrieval is influenced by spatial contextual information that determines
responding to conditioned stimuli (CS). However, it is poorly understood whether contextual …
responding to conditioned stimuli (CS). However, it is poorly understood whether contextual …
Plastic and stimulus-specific coding of salient events in the central amygdala
The central amygdala (CeA) is implicated in a range of mental processes including attention,
motivation, memory formation and extinction and in behaviours driven by either aversive or …
motivation, memory formation and extinction and in behaviours driven by either aversive or …
Holographic stimulation of opposing amygdala ensembles bidirectionally modulates valence-specific behavior via mutual inhibition
The basolateral amygdala (BLA) is an evolutionarily conserved brain region, well known for
valence processing. Despite this central role, the relationship between activity of BLA …
valence processing. Despite this central role, the relationship between activity of BLA …