CRISPR screens identify gene targets at breast cancer risk loci
Background Genome-wide association studies (GWAS) have identified> 200 loci associated
with breast cancer risk. The majority of candidate causal variants are in non-coding regions …
with breast cancer risk. The majority of candidate causal variants are in non-coding regions …
Functional annotation of breast cancer risk loci: current progress and future directions
Genome-wide association studies coupled with large-scale replication and fine-scale
map** studies have identified more than 150 genomic regions that are associated with …
map** studies have identified more than 150 genomic regions that are associated with …
Biological effects and regulation of IGFBP5 in breast cancer
J Dittmer - Frontiers in Endocrinology, 2022 - frontiersin.org
The insulin-like growth factor receptor (IGF1R) pathway plays an important role in cancer
progression. In breast cancer, the IGF1R pathway is linked to estrogen-dependent signaling …
progression. In breast cancer, the IGF1R pathway is linked to estrogen-dependent signaling …
Rare germline copy number variants (CNVs) and breast cancer risk
Germline copy number variants (CNVs) are pervasive in the human genome but potential
disease associations with rare CNVs have not been comprehensively assessed in large …
disease associations with rare CNVs have not been comprehensively assessed in large …
CRISPR screens identify gene targets and drug repositioning opportunities at breast cancer risk loci
Genome-wide association studies (GWAS) have identified> 200 loci associated with breast
cancer (BC) risk. The majority of candidate causal variants (CCVs) are in non-coding …
cancer (BC) risk. The majority of candidate causal variants (CCVs) are in non-coding …
[PDF][PDF] Capture Hi-C to identify regulatory variants and target genes influencing breast cancer risk
A Zvereva - 2022 - repository.icr.ac.uk
Genome wide association studies have discovered approximately 200 breast cancer risk
single nucleotide polymorphisms, most of which map to non-protein-coding regions. To …
single nucleotide polymorphisms, most of which map to non-protein-coding regions. To …
Rare germline copy number variants (CNVs) and breast cancer risk
D Easton - 2022 - repository.cam.ac.uk
Germline copy number variants (CNVs) are pervasive in the human genome but potential
disease associations with rare CNVs have not been comprehensively assessed in large …
disease associations with rare CNVs have not been comprehensively assessed in large …
CRISPR screens identify gene targets and drug repositioning opportunities at breast cancer risk loci
Genome-wide association studies (GWAS) have identified> 200 loci associated with breast
cancer (BC) risk. The majority of candidate causal variants (CCVs) are in non-coding …
cancer (BC) risk. The majority of candidate causal variants (CCVs) are in non-coding …
Rare copy number variants (CNVs) and breast cancer risk
Abstract Background Copy number variants (CNVs) are pervasive in the human genome but
potential disease associations with rare CNVs have not been comprehensively assessed in …
potential disease associations with rare CNVs have not been comprehensively assessed in …
[PDF][PDF] Repozytorium Pomorskiego Uniwersytetu Medycznego w Szczecinie Repository of Pomeranian Medical University in Szczecin https://ppm. pum. edu. pl
D Joe, P Tyrer Jonathan, C Walker Logan, M Kyriaki… - 2021 - ppm.pum.edu.pl
Breast cancer (BC) risk for BRCA1 and BRCA2 mutation carriers varies by genetic and
familial factors. About 50 common variants have been shown to modify BC risk for mutation …
familial factors. About 50 common variants have been shown to modify BC risk for mutation …