Detection and beyond: Challenges and advances in aptamer-based biosensors

H Yoo, H Jo, SS Oh - Materials Advances, 2020 - pubs.rsc.org
Beyond traditional needs of biosensors such as high sensitivity and selectivity for analyte
detection, newly emerging requirements including a real-time detection ability and in-field …

DNA hydrogels and microgels for biosensing and biomedical applications

F Li, D Lyu, S Liu, W Guo - Advanced Materials, 2020 - Wiley Online Library
DNA hydrogels, which take advantage of the unique properties of functional DNA motifs,
such as specific molecular recognition, programmable and high‐precision assembly …

Programmable CRISPR-responsive smart materials

MA English, LR Soenksen, RV Gayet, H de Puig… - Science, 2019 - science.org
Stimuli-responsive materials activated by biological signals play an increasingly important
role in biotechnology applications. We exploit the programmability of CRISPR-associated …

Isothermal amplification of nucleic acids

Y Zhao, F Chen, Q Li, L Wang, C Fan - Chemical reviews, 2015 - ACS Publications
Isothermal amplification of nucleic acids is a simple process that rapidly and efficiently
accumulates nucleic acid sequences at constant temperature. Since the early 1990s …

Gold nanomaterials at work in biomedicine

X Yang, M Yang, B Pang, M Vara, Y **a - Chemical reviews, 2015 - ACS Publications
Gold is a precious metal with a characteristic bright and beautiful hue known as the golden
yellow color.(1) As of 2012, a total of 174,100 tons of Au has been mined in human history …

Biomedical applications of DNA‐based hydrogels

J Gačanin, CV Synatschke… - Advanced Functional …, 2020 - Wiley Online Library
Nucleic acids are gaining significant attention as versatile building blocks for the next
generation of soft materials. Due to significant advances in the chemical synthesis and …

Aptamer-integrated DNA nanostructures for biosensing, bioimaging and cancer therapy

HM Meng, H Liu, H Kuai, R Peng, L Mo… - Chemical Society …, 2016 - pubs.rsc.org
The combination of nanostructures with biomolecules leading to the generation of functional
nanosystems holds great promise for biotechnological and biomedical applications. As a …

Self-assembling nucleic acid nanostructures functionalized with aptamers

A Krissanaprasit, CM Key, S Pontula… - Chemical …, 2021 - ACS Publications
Researchers have worked for many decades to master the rules of biomolecular design that
would allow artificial biopolymer complexes to self-assemble and function similarly to the …

Rationally engineered nucleic acid architectures for biosensing applications

M **ao, W Lai, T Man, B Chang, L Li… - Chemical …, 2019 - ACS Publications
Development of biosensing platforms plays a key role in research settings for identification
of biomarkers and in clinical applications for diagnostics. Biosensors based on nucleic acids …

Polymeric DNA hydrogel: Design, synthesis and applications

F Li, J Tang, J Geng, D Luo, D Yang - Progress in Polymer Science, 2019 - Elsevier
Deoxyribonucleic acid (DNA) stores genetic information as a biomolecule, and also is
regarded as a block copolymer and polyanion. Under favorable environments, DNA …