[HTML][HTML] Pure drug nano-assemblies: A facile carrier-free nanoplatform for efficient cancer therapy

S Fu, G Li, W Zang, X Zhou, K Shi, Y Zhai - Acta Pharmaceutica Sinica B, 2022 - Elsevier
Nanoparticulate drug delivery systems (Nano-DDSs) have emerged as possible solution to
the obstacles of anticancer drug delivery. However, the clinical outcomes and translation are …

Nasopharyngeal carcinoma

YP Chen, ATC Chan, QT Le, P Blanchard, Y Sun, J Ma - The Lancet, 2019 - thelancet.com
Nasopharyngeal carcinoma is characterised by distinct geographical distribution and is
particularly prevalent in east and southeast Asia. Epidemiological trends in the past decade …

Chemotherapy in combination with radiotherapy for definitive-intent treatment of stage II-IVA nasopharyngeal carcinoma: CSCO and ASCO guideline

YP Chen, N Ismaila, MLK Chua, AD Colevas… - Journal of Clinical …, 2021 - ascopubs.org
PURPOSE The aim of this joint guideline is to provide evidence-based recommendations to
practicing physicians and other healthcare providers on definitive-intent chemoradiotherapy …

Metronomic capecitabine as adjuvant therapy in locoregionally advanced nasopharyngeal carcinoma: a multicentre, open-label, parallel-group, randomised …

YP Chen, X Liu, Q Zhou, KY Yang, F **, XD Zhu, M Shi… - The Lancet, 2021 - thelancet.com
Background Patients with locoregionally advanced nasopharyngeal carcinoma have a high
risk of disease relapse, despite a high proportion of patients attaining complete clinical …

Disulfide bond-driven oxidation-and reduction-responsive prodrug nanoassemblies for cancer therapy

B Sun, C Luo, H Yu, X Zhang, Q Chen, W Yang… - Nano …, 2018 - ACS Publications
Disulfide bonds have been widely used to develop reduction-responsive drug-delivery
systems (DDS) for cancer therapy. We propose that disulfide bonds might be also used as …

Probing the impact of sulfur/selenium/carbon linkages on prodrug nanoassemblies for cancer therapy

B Sun, C Luo, X Zhang, M Guo, M Sun, H Yu… - Nature …, 2019 - nature.com
Tumor cells are characterized as redox-heterogeneous intracellular microenvironment due
to the simultaneous overproduction of reactive oxygen species and glutathione. Rational …

A smart theranostic prodrug system activated by reactive oxygen species for regional chemotherapy of metastatic cancer

L Liu, F Liu, D Liu, W Yuan, M Zhang… - Angewandte …, 2022 - Wiley Online Library
Metastatic cancer is difficult to cure because of its uncontrollable nature and side effects
during treatment. We constructed a reactive oxygen species (ROS)‐activated smart …

Nanotechnology in healthcare, and its safety and environmental risks

X Ma, Y Tian, R Yang, H Wang, LW Allahou… - Journal of …, 2024 - Springer
Nanotechnology holds immense promise in revolutionising healthcare, offering
unprecedented opportunities in diagnostics, drug delivery, cancer therapy, and combating …

Prodrug nanoassemblies bridged by Mono-/Di-/Tri-sulfide bonds: Exploration is for going further

Y Yang, S Zuo, J Zhang, T Liu, X Li, H Zhang, M Cheng… - Nano Today, 2022 - Elsevier
Sulfur bonds, including thioether bond and disulfide bond, have been widely used to
develop tumor redox-responsive drug delivery systems. Recently, trisulfide bond was also …

[HTML][HTML] On the design principles of peptide–drug conjugates for targeted drug delivery to the malignant tumor site

EI Vrettos, G Mező, AG Tzakos - Beilstein journal of organic …, 2018 - beilstein-journals.org
Cancer is the second leading cause of death affecting nearly one in two people, and the
appearance of new cases is projected to rise by> 70% by 2030. To effectively combat the …