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[HTML][HTML] Pure drug nano-assemblies: A facile carrier-free nanoplatform for efficient cancer therapy
S Fu, G Li, W Zang, X Zhou, K Shi, Y Zhai - Acta Pharmaceutica Sinica B, 2022 - Elsevier
Nanoparticulate drug delivery systems (Nano-DDSs) have emerged as possible solution to
the obstacles of anticancer drug delivery. However, the clinical outcomes and translation are …
the obstacles of anticancer drug delivery. However, the clinical outcomes and translation are …
Nasopharyngeal carcinoma
Nasopharyngeal carcinoma is characterised by distinct geographical distribution and is
particularly prevalent in east and southeast Asia. Epidemiological trends in the past decade …
particularly prevalent in east and southeast Asia. Epidemiological trends in the past decade …
Chemotherapy in combination with radiotherapy for definitive-intent treatment of stage II-IVA nasopharyngeal carcinoma: CSCO and ASCO guideline
PURPOSE The aim of this joint guideline is to provide evidence-based recommendations to
practicing physicians and other healthcare providers on definitive-intent chemoradiotherapy …
practicing physicians and other healthcare providers on definitive-intent chemoradiotherapy …
Metronomic capecitabine as adjuvant therapy in locoregionally advanced nasopharyngeal carcinoma: a multicentre, open-label, parallel-group, randomised …
Background Patients with locoregionally advanced nasopharyngeal carcinoma have a high
risk of disease relapse, despite a high proportion of patients attaining complete clinical …
risk of disease relapse, despite a high proportion of patients attaining complete clinical …
Disulfide bond-driven oxidation-and reduction-responsive prodrug nanoassemblies for cancer therapy
B Sun, C Luo, H Yu, X Zhang, Q Chen, W Yang… - Nano …, 2018 - ACS Publications
Disulfide bonds have been widely used to develop reduction-responsive drug-delivery
systems (DDS) for cancer therapy. We propose that disulfide bonds might be also used as …
systems (DDS) for cancer therapy. We propose that disulfide bonds might be also used as …
Probing the impact of sulfur/selenium/carbon linkages on prodrug nanoassemblies for cancer therapy
B Sun, C Luo, X Zhang, M Guo, M Sun, H Yu… - Nature …, 2019 - nature.com
Tumor cells are characterized as redox-heterogeneous intracellular microenvironment due
to the simultaneous overproduction of reactive oxygen species and glutathione. Rational …
to the simultaneous overproduction of reactive oxygen species and glutathione. Rational …
A smart theranostic prodrug system activated by reactive oxygen species for regional chemotherapy of metastatic cancer
L Liu, F Liu, D Liu, W Yuan, M Zhang… - Angewandte …, 2022 - Wiley Online Library
Metastatic cancer is difficult to cure because of its uncontrollable nature and side effects
during treatment. We constructed a reactive oxygen species (ROS)‐activated smart …
during treatment. We constructed a reactive oxygen species (ROS)‐activated smart …
Nanotechnology in healthcare, and its safety and environmental risks
Nanotechnology holds immense promise in revolutionising healthcare, offering
unprecedented opportunities in diagnostics, drug delivery, cancer therapy, and combating …
unprecedented opportunities in diagnostics, drug delivery, cancer therapy, and combating …
Prodrug nanoassemblies bridged by Mono-/Di-/Tri-sulfide bonds: Exploration is for going further
Y Yang, S Zuo, J Zhang, T Liu, X Li, H Zhang, M Cheng… - Nano Today, 2022 - Elsevier
Sulfur bonds, including thioether bond and disulfide bond, have been widely used to
develop tumor redox-responsive drug delivery systems. Recently, trisulfide bond was also …
develop tumor redox-responsive drug delivery systems. Recently, trisulfide bond was also …
[HTML][HTML] On the design principles of peptide–drug conjugates for targeted drug delivery to the malignant tumor site
Cancer is the second leading cause of death affecting nearly one in two people, and the
appearance of new cases is projected to rise by> 70% by 2030. To effectively combat the …
appearance of new cases is projected to rise by> 70% by 2030. To effectively combat the …