Owing to their tunable properties, controllable degradation, and ability to protect labile
drugs, hydrogels are increasingly investigated as local drug delivery systems. However, a …

The development of new high-tech systems for screening anticancer drugs is one of the
main problems of preclinical screening. Poor correlation between preclinical in vitro and in …

Chronic lung diseases (CLDs) are regulated by complex interactions between many
different cell types residing in lung airway tissues. Specifically, interactions between airway …

Myeloid-derived suppressor cells (MDSCs) play a major role in cancer progression. In this
study, we investigated the mechanisms by which complement C5a increases the capacity of …

The lack of traditional cancer treatments has resulted in an increased need for new clinical
techniques. Standard two-dimensional (2D) models used to validate drug efficacy and …

This review aims to show case recent regenerative medicine based on biomaterial
technologies. Regenerative medicine has arousing substantial interest throughout the world …

Metastases, or migration of cancers, are common and severe cancer complications.
Although the 5-year survival rates of primary tumors have greatly improved, those of …

An early step of metastasis requires a complex and coordinated migration of invasive tumor
cells into the surrounding tumor microenvironment (TME), which contains extracellular …

Platelets extravasate from the circulation into tumor microenvironment, enable metastasis,
and confer resistance to chemotherapy in several cancers. Therefore, arresting tumor …

Neural tissue engineering (NTE) has made remarkable strides in recent years and holds
great promise for treating several devastating neurological disorders. Selecting optimal …