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Airflow and particle transport in the human respiratory system
C Kleinstreuer, Z Zhang - Annual review of fluid mechanics, 2010 - annualreviews.org
Airflows in the nasal cavities and oral airways are rather complex, possibly featuring a
transition to turbulent jet-like flow, recirculating flow, Dean's flow, vortical flows, large …
transition to turbulent jet-like flow, recirculating flow, Dean's flow, vortical flows, large …
Deposition of inhaled particles in the lungs
AF Tena, PC Clarà - Archivos de Bronconeumología (English Edition), 2012 - Elsevier
Inhaled medication is the first-line treatment of diseases such as asthma or chronic
obstructive pulmonary disease. Its effectiveness is related to the amount of drug deposited …
obstructive pulmonary disease. Its effectiveness is related to the amount of drug deposited …
Flow structure and particle deposition analyses for optimization of a pressurized metered dose inhaler (pMDI) in a model of tracheobronchial airway
Inhalation therapy plays an important role in management or treatment of respiratory
diseases such asthma and chronic obstructive pulmonary diseases (COPDs). For decades …
diseases such asthma and chronic obstructive pulmonary diseases (COPDs). For decades …
Modeling airflow and particle transport/deposition in pulmonary airways
C Kleinstreuer, Z Zhang, Z Li - Respiratory physiology & neurobiology, 2008 - Elsevier
A review of research papers is presented, pertinent to computer modeling of airflow as well
as nano-and micron-size particle deposition in pulmonary airway replicas. The key modeling …
as nano-and micron-size particle deposition in pulmonary airway replicas. The key modeling …
On intra-and intersubject variabilities of airflow in the human lungs
The effects of intra-and intersubject variabilities in airway geometry on airflow in the human
lungs are investigated by large eddy simulation. The airway models of two human subjects …
lungs are investigated by large eddy simulation. The airway models of two human subjects …
Fabrication of rigid and flexible refractive-index-matched flow phantoms for flow visualisation and optical flow measurements
A method for the construction of both rigid and compliant (flexible) transparent flow
phantoms of biological flow structures, suitable for PIV and other optical flow methods with …
phantoms of biological flow structures, suitable for PIV and other optical flow methods with …
Dry powder inhaler aerosol deposition in a model of tracheobronchial airways: Validating CFD predictions with in vitro data
Effective drug delivery into the lungs plays an important role in management of pulmonary
diseases that affect millions all around the world. The main objective of this investigation is …
diseases that affect millions all around the world. The main objective of this investigation is …
Numerical study of high-frequency oscillatory air flow and convective mixing in a CT-based human airway model
High-frequency oscillatory ventilation (HFOV) is considered an efficient and safe respiratory
technique to ventilate neonates and patients with acute respiratory distress syndrome. HFOV …
technique to ventilate neonates and patients with acute respiratory distress syndrome. HFOV …
Development of a realistic human airway model
Numerous models of human lungs with various levels of idealization have been reported in
the literature; consequently, results acquired using these models are difficult to compare to …
the literature; consequently, results acquired using these models are difficult to compare to …
Experimental methods for flow and aerosol measurements in human airways and their replicas
Recent developments in the prediction of local aerosol deposition in human lungs are driven
by the fast development of computational simulations. Although such simulations provide …
by the fast development of computational simulations. Although such simulations provide …