Adult epilepsy

AA Asadi-Pooya, F Brigo, S Lattanzi, I Blumcke - The Lancet, 2023 - thelancet.com
Epilepsy is a common medical condition that affects people of all ages, races, social classes,
and geographical regions. Diagnosis of epilepsy remains clinical, and ancillary …

Management of epilepsy in pregnancy: a report from the International League Against Epilepsy Task Force on Women and Pregnancy

T Tomson, D Battino, R Bromley, S Kochen… - Epileptic …, 2019 - shs.cairn.info
Management of epilepsy in pregnancy: a report from the International League Against Epilepsy
Task Force on Women and Pregnancy | Cairn.info Cairn.info, Matières à réflexion Cairn.info …

[PDF][PDF] Congenital heart disease, prenatal diagnosis and management

CH Meller, S Grinenco, H Aiello, A Córdoba… - Arch Argent …, 2020 - sap.org.ar
Among congenital malformations, heart defects are the most common type of anomaly, and
these are associated with a high perinatal, longterm morbidity and mortality. The objective of …

Production of human spinal-cord organoids recapitulating neural-tube morphogenesis

JH Lee, H Shin, MR Shaker, HJ Kim, SH Park… - Nature Biomedical …, 2022 - nature.com
Human spinal-cord-like tissues induced from human pluripotent stem cells are typically
insufficiently mature and do not mimic the morphological features of neurulation. Here, we …

Antiepileptic drug monotherapy for epilepsy: a network meta‐analysis of individual participant data

SJ Nevitt, M Sudell, S Cividini… - Cochrane Database …, 2022 - cochranelibrary.com
Objectives To compare the time to treatment failure, remission and first seizure of 12 AEDs
(carbamazepine, phenytoin, sodium valproate, phenobarbitone, oxcarbazepine, lamotrigine …

[HTML][HTML] Valproic acid in pregnancy revisited: neurobehavioral, biochemical and molecular changes affecting the embryo and fetus in humans and in animals: a …

A Ornoy, B Echefu, M Becker - International Journal of Molecular Sciences, 2023 - mdpi.com
Valproic acid (VPA) is a very effective anticonvulsant and mood stabilizer with relatively few
side effects. Being an epigenetic modulator, it undergoes clinical trials for the treatment of …

Epilepsy and pregnancy

Y Li, KJ Meador - CONTINUUM: Lifelong learning in neurology, 2022 - journals.lww.com
PURPOSE OF REVIEW Seizure disorders are the most frequent major neurologic
complication in pregnancy, affecting 0.3% to 0.8% of all gestations. Women of childbearing …

30 years of second-generation antiseizure medications: impact and future perspectives

E Perucca, MJ Brodie, P Kwan, T Tomson - The Lancet Neurology, 2020 - thelancet.com
Summary Since 1989, 18 second-generation antiseizure medications have reached the
market, resulting in a greatly increased range of treatment options for patients and …

Interventions during pregnancy to prevent preterm birth: an overview of Cochrane systematic reviews

N Medley, JP Vogel, A Care… - Cochrane Database of …, 2018 - cochranelibrary.com
Background Preterm birth (PTB) is a major factor contributing to global rates of neonatal
death and to longer‐term health problems for surviving infants. Both the World Health …

Brain tumor-related epilepsy management: A Society for Neuro-oncology (SNO) consensus review on current management

EK Avila, S Tobochnik, SK Inati, JAF Koekkoek… - Neuro …, 2024 - academic.oup.com
Tumor-related epilepsy (TRE) is a frequent and major consequence of brain tumors.
Management of TRE is required throughout the course of disease and a deep …