Immune response in COVID-19: what is next?
Abstract The coronavirus disease 2019 (COVID-19) has been a global pandemic for more
than 2 years and it still impacts our daily lifestyle and quality in unprecedented ways. A …
than 2 years and it still impacts our daily lifestyle and quality in unprecedented ways. A …
Chemical Biology of H2S Signaling through Persulfidation
Signaling by H2S is proposed to occur via persulfidation, a posttranslational modification of
cysteine residues (RSH) to persulfides (RSSH). Persulfidation provides a framework for …
cysteine residues (RSH) to persulfides (RSSH). Persulfidation provides a framework for …
Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …
Hydrogen sulfide-based therapeutics: exploiting a unique but ubiquitous gasotransmitter
Hydrogen sulfide (H2S) has become recognized as an important signalling molecule
throughout the body, contributing to many physiological and pathological processes. In …
throughout the body, contributing to many physiological and pathological processes. In …
A review of hydrogen sulfide synthesis, metabolism, and measurement: is modulation of hydrogen sulfide a novel therapeutic for cancer?
Abstract Significance: Hydrogen sulfide (H2S) has been recognized as the third gaseous
transmitter alongside nitric oxide and carbon monoxide. In the past decade, numerous …
transmitter alongside nitric oxide and carbon monoxide. In the past decade, numerous …
H2S signalling through protein sulfhydration and beyond
Hydrogen sulfide (H2S) has recently emerged as a mammalian gaseous messenger
molecule, akin to nitric oxide and carbon monoxide. H2S is predominantly formed from Cys …
molecule, akin to nitric oxide and carbon monoxide. H2S is predominantly formed from Cys …
International union of basic and clinical pharmacology. CII: pharmacological modulation of H2S levels: H2S donors and H2S biosynthesis inhibitors
Over the last decade, hydrogen sulfide (H 2 S) has emerged as an important endogenous
gasotransmitter in mammalian cells and tissues. Similar to the previously characterized …
gasotransmitter in mammalian cells and tissues. Similar to the previously characterized …
[HTML][HTML] Effects of hydrogen sulfide on mitochondrial function and cellular bioenergetics
Hydrogen sulfide (H 2 S) was once considered to have only toxic properties, until it was
discovered to be an endogenous signaling molecule. The effects of H 2 S are dose …
discovered to be an endogenous signaling molecule. The effects of H 2 S are dose …
[HTML][HTML] Cysteine metabolic circuitries: druggable targets in cancer
To enable survival in adverse conditions, cancer cells undergo global metabolic
adaptations. The amino acid cysteine actively contributes to cancer metabolic remodelling …
adaptations. The amino acid cysteine actively contributes to cancer metabolic remodelling …
Regulators of the transsulfuration pathway
The transsulfuration pathway is a metabolic pathway where transfer of sulfur from
homocysteine to cysteine occurs. The pathway leads to the generation of several sulfur …
homocysteine to cysteine occurs. The pathway leads to the generation of several sulfur …