Platelet-derived growth factors (PDGF) promotes cell proliferation, survival and migration,
primarily of cells of mesenchymal origin. Dysfunction of PDGF signaling has been observed …

Atherosclerosis, the principal cause of heart attack, stroke and gangrene of the extremities,
is responsible for 50% of all mortality in the USA, Europe and Japan. The lesions result from …

The focus of this review is to provide an overview of the current state of knowledge of
molecular mechanisms/processes that control differentiation of vascular smooth muscle cells …

See also Machin SJ, Briggs C. Mean platelet volume: a quick, easy determinant of
thrombotic risk? This issue, pp 146–7. Summary. Aim: To determine whether an association …

QFJCIRLUMZQUOT-HPLJOQBZSA-N sirolimus Chemical compound C1C [C@@ H](O)[C@
H](OC) C [C@@ H] 1C [C@@ H](C)[C@ H] 1OC (= O)[C@@ H] 2CCCCN2C (= O) C …

Platelet-derived growth factors (PDGFs) and their receptors (PDGFRs) have served as
prototypes for growth factor and receptor tyrosine kinase function for more than 25 years …

Platelet-derived growth factor (PDGF) is a major mitogen for connective tissue cells and
certain other cell types. It is a dimeric molecule consisting of disulfide-bonded, structurally …

The founding member of the lipoprotein receptor family, low-density lipoprotein receptor
(LDLR) plays a major role in the atherogenesis through the receptor-mediated endocytosis …

The vessel wall is an active, integrated organ composed of endothelial, smooth-muscle, and
fibroblast cells coupled to each other in a complex autocrine-paracrine set of interactions …

Medical devices, and in particular implantable medical devices, including self-expanding
stents, may be coated to minimize or Substantially eliminate a biological organism's reaction …