Structure, assembly, and function of tripartite efflux and type 1 secretion systems in gram-negative bacteria

I Alav, J Kobylka, MS Kuth, KM Pos, M Picard… - Chemical …, 2021 - ACS Publications
Tripartite efflux pumps and the related type 1 secretion systems (T1SSs) in Gram-negative
organisms are diverse in function, energization, and structural organization. They form …

Salmonella enterica serovar Typhimurium skills to succeed in the host: virulence and regulation

A Fàbrega, J Vila - Clinical microbiology reviews, 2013 - Am Soc Microbiol
Salmonella enterica serovar Typhimurium is a primary enteric pathogen infecting both
humans and animals. Infection begins with the ingestion of contaminated food or water so …

Identification of protein secretion systems in bacterial genomes

SS Abby, J Cury, J Guglielmini, B Néron, M Touchon… - Scientific reports, 2016 - nature.com
Bacteria with two cell membranes (diderms) have evolved complex systems for protein
secretion. These systems were extensively studied in some model bacteria, but the …

Evolutionary causes and consequences of bacterial antibiotic persistence

E Bakkeren, M Diard, WD Hardt - Nature Reviews Microbiology, 2020 - nature.com
Antibiotic treatment failure is of growing concern. Genetically encoded resistance is key in
driving this process. However, there is increasing evidence that bacterial antibiotic …

RNA-seq Brings New Insights to the Intra-Macrophage Transcriptome of Salmonella Typhimurium

S Srikumar, C Kröger, M Hébrard, A Colgan… - PLoS …, 2015 - journals.plos.org
Salmonella enterica serovar Typhimurium is arguably the world's best-understood bacterial
pathogen. However, crucial details about the genetic programs used by the bacterium to …

The dynamics of gut‐associated microbial communities during inflammation

SE Winter, CA Lopez, AJ Bäumler - EMBO reports, 2013 - embopress.org
Our intestine is host to a large microbial community (microbiota) that educates the immune
system and confers niche protection. Profiling of the gut‐associated microbial community …

Salmonella–Host Interactions – Modulation of the Host Innate Immune System

D Hurley, MP McCusker, S Fanning… - Frontiers in …, 2014 - frontiersin.org
Salmonella enterica (S. enterica) are Gram-negative bacteria that can invade a broad range
of hosts causing both acute and chronic infections. This phenotype is related to its ability to …

Salmonella – the ultimate insider. Salmonella virulence factors that modulate intracellular survival

JA Ibarra, O Steele‐Mortimer - Cellular microbiology, 2009 - Wiley Online Library
Salmonella enterica serovar Typhimurium is a common facultative intracellular pathogen
that causes food‐borne gastroenteritis in millions of people worldwide. Intracellular survival …

Virulence Factors in Salmonella Typhimurium: The Sagacity of a Bacterium

AMP Dos Santos, RG Ferrari, CA Conte-Junior - Current microbiology, 2019 - Springer
Abstract Currently, Salmonella enterica Typhimurium (ST) is responsible for most cases of
food poisoning in several countries. It is characterized as a non-specific zoonotic bacterium …

[HTML][HTML] Salmonella effector driven invasion of the gut epithelium: breaking in and setting the house on fire

SA Fattinger, ME Sellin, WD Hardt - Current Opinion in Microbiology, 2021 - Elsevier
Highlights•IEC invasion is a crucial step in the life cycle of non-typhoidal Salmonella.•TTSS-
1 effectors SopE/E2 and particularly SipA mediate IEC invasion in mice.•Entry structures …