Gene expression is central to the genotype-phenotype relationship in all organisms, and it is
an important component of the genetic basis for evolutionary change in diverse aspects of …

During organogenesis, the endoderm forms the epithelial lining of the primitive gut tube from
which the alimentary canal and associated organs, such as the liver and pancreas, develop …

Tissue-specific gene expression is fundamental in development and evolution, and is
mediated by transcription factors and by the cis-regulatory regions (enhancers) that they …

The Drosophila hindgut is fruitful territory for investigation of events common to many types
of organogenesis. The development of the Drosophila hindgut provides, in microcosm, a …

Joseph C. Corbo, 1, 3 Anna Di Gregorio, 2 and Michael Levine2, 3 1Department of
Pathology Brigham and Women's Hospital and Harvard Medical School Boston …

Abstract Setting up future body axes is the first important event before and at the beginning
of embryogenesis. The ascidian embryo is a classic model that has been used to gain …

Ascidian metamorphosis represents a powerful model for comparative work on chordate
development that has remained largely unexplored. We isolated transcripts differentially …

Thanks to their transparent and rapidly develo** mosaic embryos, ascidians (or sea
squirts) have been a model system for embryological studies for over a century. Recently …

Transcription factors (TFs) are DNA-binding proteins able to modulate the timing, location,
and levels of gene expression by binding to regulatory DNA regions. Therefore, the …

Endoderm differentiation and movements are of fundamental importance not only for
subsequent morphogenesis of the digestive tract but also to enable normal patterning and …