Shining new light on biological systems: luminescent transition metal complexes for bioimaging and biosensing applications

LCC Lee, KKW Lo - Chemical Reviews, 2024 - ACS Publications
Luminescence imaging is a powerful and versatile technique for investigating cell
physiology and pathology in living systems, making significant contributions to life science …

Metallodrugs in cancer nanomedicine

Q Peña, A Wang, O Zaremba, Y Shi… - Chemical society …, 2022 - pubs.rsc.org
Metal complexes are extensively used for cancer therapy. The multiple variables available
for tuning (metal, ligand, and metal–ligand interaction) offer unique opportunities for drug …

[HTML][HTML] Extracellular vesicle-based drug delivery systems for cancer treatment

S Walker, S Busatto, A Pham, M Tian, A Suh… - Theranostics, 2019 - ncbi.nlm.nih.gov
Extracellular vesicles (EVs) are naturally occurring cell-secreted nanoparticles that play
important roles in many physiological and pathological processes. EVs enable intercellular …

The development of anticancer ruthenium (II) complexes: from single molecule compounds to nanomaterials

L Zeng, P Gupta, Y Chen, E Wang, L Ji… - Chemical Society …, 2017 - pubs.rsc.org
Cancer is rapidly becoming the top killer in the world. Most of the FDA approved anticancer
drugs are organic molecules, while metallodrugs are very scarce. The advent of the first …

[HTML][HTML] Multifunctional magnetic iron oxide nanoparticles: an advanced platform for cancer theranostics

S Zhao, X Yu, Y Qian, W Chen, J Shen - Theranostics, 2020 - ncbi.nlm.nih.gov
Multifunctional magnetic nanoparticles and derivative nanocomposites have aroused great
concern for multimode imaging and cancer synergistic therapies in recent years. Among the …

Ru (II) compounds: next-generation anticancer metallotherapeutics?

S Thota, DA Rodrigues, DC Crans… - Journal of medicinal …, 2018 - ACS Publications
Metal based therapeutics are a precious class of drugs in oncology research that include
examples of theranostic drugs, which are active in both diagnostic, specifically imaging, and …

Current state of breast cancer diagnosis, treatment, and theranostics

A Bhushan, A Gonsalves, JU Menon - Pharmaceutics, 2021 - mdpi.com
Breast cancer is one of the leading causes of cancer-related morbidity and mortality in
women worldwide. Early diagnosis and effective treatment of all types of cancers are crucial …

The development of ruthenium (II) polypyridyl complexes and conjugates for in vitro cellular and in vivo applications

FE Poynton, SA Bright, S Blasco, DC Williams… - Chemical Society …, 2017 - pubs.rsc.org
Ruthenium (II)[Ru (II)] polypyridyl complexes have been the focus of intense investigations
since work began exploring their supramolecular interactions with DNA. In recent years …

Recent trends of the bio-inspired nanoparticles in cancer theranostics

VS Madamsetty, A Mukherjee… - Frontiers in …, 2019 - frontiersin.org
In recent years, various nanomaterials have emerged as an exciting tool in cancer
theranostic applications due to their multifunctional property and intrinsic molecular property …

Current advances in the use of exosomes, liposomes, and bioengineered hybrid nanovesicles in cancer detection and therapy

A Mukherjee, B Bisht, S Dutta, MK Paul - Acta Pharmacologica Sinica, 2022 - nature.com
Three major approaches of cancer therapy can be enunciated as delivery of biotherapeutics,
tumor image analysis, and immunotherapy. Liposomes, artificial fat bubbles, are long known …