Neurotoxin-derived optical probes for biological and medical imaging

PH Ergen, S Shorter, V Ntziachristos… - Molecular Imaging and …, 2023 - Springer
The superb specificity and potency of biological toxins targeting various ion channels and
receptors are of major interest for the delivery of therapeutics to distinct cell types and …

Three-dimensional structure of human voltage-gated ion channel Kv10. 2 studied by electron microscopy of macromolecules and molecular modeling

OS Sokolova, KV Shaitan, AV Grizel… - Russian Journal of …, 2012 - Springer
Three-dimensional structure of the human voltage-gated channel Kv10. 2 has been
elucidated for the first time using the method of electron microscopy with 2.5 nm resolution …

The structure of a human voltage-gated potassium Kv10. 2 channel which lacks a cytoplasmic pas domain

GS Glukhov, AV Popinako, AV Grizel, KV Shaitan… - Biophysics, 2016 - Springer
The three-dimensional structure of a human voltage-gated potassium Kv10. 2 channel which
lacks a cytoplasmic N-terminal PAS-domain was determined, and its distribution in …

Molecular modeling of the tetramerization domain of human potassium channel Kv10. 2 in different oligomeric states

VN Novoseletsky, AD Volyntseva, KV Shaitan… - Moscow University …, 2017 - Springer
A voltage-gated potassium channel Kv10. 2 is expressed in the nervous system, but its
functions and involvement in the development of human disease remain poorly understood …

Influence of interionic interactions on functional state and blocker binding of voltage-gated potassium channels

KV Shaitan, OS Sokolova, AK Shaitan… - Moscow University …, 2013 - Springer
A mechanism of ion conduction of a voltage-gated potassium channel KcsA was
investigated in full-atomic approximation at a trajectory length of 100 ns using the …

[PDF][PDF] Трехмерная структура потенциалзависимого человеческого канала Kv10. 2 по данным электронной микроскопии макромолекул и молекулярного …

ОС Соколова, КВ Шайтан, АВ Гризель… - Биоорганическая …, 2012 - istina.msu.ru
Методом электронной микроскопии впервые получена трехмерная структура
человеческого потен циалзависимого канала Kv10. 2 с разрешением 2.5 нм. Молекула …

Investigation of potassium channels in neurons and nerve fibers using a quantum-dot-potassium-channel-blocker complex

TA Kazakova, MG Karlova, OS Sokolova… - Nanotechnologies in …, 2015 - Springer
A fluorescent complex comprising semiconductor nanocrystals (CdTe quantum dots) and a
potassium channel blocker, agitoxin (AgTx), is suggested for investigating the allocation of …

[PDF][PDF] MOLECULAR MECHANISMS OF TRANSCRIPTION THROUGH CHROMATIN BY RNA POLYMERASE III

VM Studitsky, IV Orlovsky, OV Chertkov… - НАУЧНЫЙ …, 2012 - vestnik-bio-msu.elpub.ru
The nucleosome forms the so-called “nucleosome barrier”, which presents a serious
obstacle to the transcription machinery. We consider the study of formation and overcoming …

[PDF][PDF] INFLUENCE OF INTERIONIC INTERACTIONS ON FUNCTIONAL STATE OF KV CHANNELS AND ON BLOCKER BINDING

KV Shaitan, OS Sokolova, AK Shaitan… - НАУЧНЫЙ …, 2012 - vestnik-bio-msu.elpub.ru
In this study we estimate the ionic current of voltage-gated potassium channel KcsA (all-
atom model) on 100 ns trajectories and interactions of mammalian voltage-gated channel …

Молекулярное моделирование пространственной структуры тетрамеризационного домена калиевого канала Kv10. 2 человека в различных олигомерных …

ВН Новоселецкий, АД Волынцева… - … . Серия 16. Биология, 2017 - cyberleninka.ru
Потенциал-управляемый калиевый канал Kv10. 2 экспрессируется в нервной системе,
однако его функции и участие в развитии болезней человека остаются мало …