Naturally occurring polymers, particularly of the polysaccharide type, have been used
pharmaceutically for the delivery of a wide variety of therapeutic agents. Chitosan, the …

Hydrogels are the most iconic class of soft materials, and since their first report in the
literature, they have attracted the attention of uncountable researchers. Over the past two …

To improve the efficacy of chemotherapy and relieve the pain associated with colorectal
cancer, a dual-drug delivery system (DDDS) is proposed. In this system, methotrexate (MTX) …

Chitosan has prompted the continuous impetus for the development of safe and effective
drug delivery systems because of its unique physicochemical and biological characteristics …

Chitosan, a natural cationic polysaccharide, is prepared industrially by the hydrolysis of the
aminoacetyl groups of chitin, a naturally available marine polymer. Chitosan is a non-toxic …

The ability to deliver drugs to the human colon in a specific manner has become feasible
over the years. Targeting pharmaceutical drugs to the colon makes it possible to achieve …

Role of gut microbiome in obesity and type 2 diabetes (T2D) became apparent from several
independent studies indicating that gut microbiome modulators like prebiotics may improve …

Chitosan has prompted the continuous movement for the development of safe and effective
drug delivery systems because of its unique physicochemical and biological characteristics …

Highlights•Overview of colonic drug delivery systems.•Potential for local and systemic
delivery.•Key focus on metabolic activity of the colonic microbiota.•Challenges of microbiota …

In the present study, Eudragit S100 coated Citrus Pectin Nanoparticles (E-CPNs) were
prepared for the colon targeting of 5-Fluorouracil (5-FU). Citrus pectin also acts as a ligand …