Blood fibrinogen as a biomarker of chronic obstructive pulmonary disease

A Duvoix, J Dickens, I Haq, D Mannino, B Miller… - Thorax, 2013 - thorax.bmj.com
Background Chronic obstructive pulmonary disease (COPD) is a multicomponent condition
that is characterised by airflow obstruction that is not fully reversible and is a major global …

A systematic review of diagnostic biomarkers of COPD exacerbation

YWR Chen, JM Leung, DD Sin - PloS one, 2016 - journals.plos.org
The aims of this systematic review were to determine which blood-based molecules have
been evaluated as possible biomarkers to diagnose chronic obstructive pulmonary disease …

Exacerbations of Chronic Obstructive Pulmonary Disease and Cardiac Events. A Post Hoc Cohort Analysis from the SUMMIT Randomized Clinical Trial

KM Kunisaki, MT Dransfield, JA Anderson… - American journal of …, 2018 - atsjournals.org
Rationale: Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are
common, associated with acute inflammation, and may increase subsequent cardiovascular …

Serum uric acid as a predictor of mortality and future exacerbations of COPD

K Bartziokas, AI Papaioannou… - European …, 2013 - publications.ersnet.org
Serum uric acid is increased in respiratory disease, especially in the presence of hypoxia
and systemic inflammation. We evaluated serum uric acid as a biomarker for prediction of …

Is it possible to identify exacerbations of mild to moderate COPD that do not require antibiotic treatment?

M Miravitlles, A Moragas, S Hernández, C Bayona… - Chest, 2013 - Elsevier
Background Anthonisen criteria are widely used to guide the use of antibiotics in
exacerbations of COPD. We evaluated the best predictors of outcomes in exacerbations of …

Oxidative stress and macrophages: driving forces behind exacerbations of asthma and chronic obstructive pulmonary disease?

LES de Groot, TA Van Der Veen… - … of physiology-lung …, 2019 - journals.physiology.org
Oxidative stress is a common feature of obstructive airway diseases like asthma and chronic
obstructive pulmonary disease (COPD). Lung macrophages are key innate immune cells …

[HTML][HTML] Oxidative and nitrosative stress and histone deacetylase-2 activity in exacerbations of COPD

J Footitt, P Mallia, AL Durham, WE Ho… - Chest, 2016 - Elsevier
Background Respiratory virus infections are commonly associated with COPD
exacerbations, but little is known about the mechanisms linking virus infection to …

Increased risk of major adverse cardiac events following the onset of acute exacerbations of COPD

M Reilev, A Pottegård, J Lykkegaard… - …, 2019 - Wiley Online Library
Background and objective Acute exacerbations in chronic obstructive pulmonary disease
(COPD) may trigger major adverse cardiac events (MACE). We aimed to determine whether …

[HTML][HTML] Plasma leptin and adiponectin in COPD exacerbations: associations with inflammatory biomarkers

G Krommidas, K Kostikas, G Papatheodorou… - Respiratory …, 2010 - Elsevier
BACKGROUND: Various systemic inflammatory markers have been evaluated for their value
in acute exacerbations of chronic obstructive pulmonary disease (COPD). Leptin and …

The role of microparticles in chronic obstructive pulmonary disease

T Takahashi, H Kubo - International journal of chronic obstructive …, 2014 - Taylor & Francis
Accumulating evidence suggests that cell injury in lung tissues is closely connected to
disease progression in chronic obstructive pulmonary disease (COPD). Microparticles (MPs) …