In contrast to the programmed nature of development, it is still a matter of debate whether
aging is an adaptive and regulated process, or merely a consequence arising from a …

In mitotic cells, cellular senescence is a permanent state of G1 arrest, that may have evolved
in parallel to apoptosis, to limit proliferation of damaged cells and oncogenesis. Recent …

The first clinical symptoms focused on the presentation of coronavirus disease 2019 (COVID-
19) have been respiratory failure, however, accumulating evidence also points to its …

Alzheimer's Disease (AD), a progressive and debilitating condition, is reported to be the
most common type of dementia, with at least 55 million people believed to be currently …

Environmental factors such as chemicals, stress and pathogens are now widely believed to
play important roles in the onset of some brain diseases, as they are associated with …

Commencing lifelong antiretroviral therapy (ART) immediately following HIV diagnosis
(Option B+) has dramatically improved the health of HIV-infected women and their children …

With the advent of antiretroviral therapy (ART), HIV‐infected individuals are now living
longer and healthier lives. However, ART does not completely restore health and treated …

The brain is particularly sensitive to changes in energy supply. Defects in glucose utilization
and mitochondrial dysfunction are hallmarks of nearly all neurodegenerative diseases and …

Posttranslational modification and agglomeration of α-synuclein (α-Syn), mitochondrial
dysfunction, oxidative stress and loss of dopaminergic neurons are hallmark of Parkinson's …

Despite the promising therapeutic effects of combinatory antiretroviral therapy (cART), 20%
to 30% of HIV/AIDS patients living with long term infection still exhibit related cognitive and …