Platelets—blood cells continuously produced from megakaryocytes mainly in the bone
marrow—are implicated not only in haemostasis and arterial thrombosis, but also in other …

Complete blood count (CBC) is one of the most common blood tests requested by clinicians
and evaluates the total numbers and characteristics of cell components in the blood …

Bioadhesives reduce operation time and surgical complications. However, in the presence
of blood, adhesion strength is often compromised. Inspired by the blood clotting activity of …

Multiple mechanisms mediate thrombin generation and consequently the thrombin
concentration present during fibrin formation. First, the levels of pro-and anticoagulants …

Pulmonary thrombosis is a significant cause of patient mortality; however, there are no
effective in vitro models of thrombi formation in human lung microvessels that could also …

Antiplatelet drugs, such as aspirin, P2Y12 antagonists, and glycoprotein (GP) IIb/IIIa
inhibitors, have proved to be successful in reducing the morbidity and mortality associated …

A State of the Art lecture titled “Blood Clot Contraction: Mechanisms, Pathophysiology, and
Disease” was presented at the International Society on Thrombosis and Haemostasis (ISTH) …

Hemostasis requires the tightly regulated interaction of the coagulation system, platelets,
other blood cells and components of the vessel wall at a site of vascular injury. The …

While hemostasis is the physiological process that prevents blood loss after vessel injury,
thrombosis is often portrayed as a pathologic event involving blood coagulation and platelet …

Although platelets are best known for their role in hemostasis, they are also crucial in
development, host defense, inflammation, and tissue repair. Many of these roles are …