Therapeutic potential of cannabis, cannabidiol, and cannabinoid-based pharmaceuticals
Background: There is a growing interest in the use of cannabis (and its extracts), as well as
CBD oil (hemp extracts containing cannabidiol), for therapeutic purposes. While there is …
CBD oil (hemp extracts containing cannabidiol), for therapeutic purposes. While there is …
The pharmacokinetics and the pharmacodynamics of cannabinoids
There is increasing interest in the use of cannabinoids for disease and symptom
management, but limited information available regarding their pharmacokinetics and …
management, but limited information available regarding their pharmacokinetics and …
[HTML][HTML] Cannabinoids in the treatment of epilepsy: hard evidence at last?
E Perucca - Journal of epilepsy research, 2017 - ncbi.nlm.nih.gov
The interest in cannabis-based products for the treatment of refractory epilepsy has
skyrocketed in recent years. Marijuana and other cannabis products with high content in Δ …
skyrocketed in recent years. Marijuana and other cannabis products with high content in Δ …
Therapeutic and clinical foundations of cannabidiol therapy for difficult-to-treat seizures in children and adults with refractory epilepsies
DS Reddy - Experimental neurology, 2023 - Elsevier
Novel and effective antiseizure medications are needed to treat refractory and rare forms of
epilepsy. Cannabinoids, which are obtained from the cannabis plant, have a long history of …
epilepsy. Cannabinoids, which are obtained from the cannabis plant, have a long history of …
Cannabis and its secondary metabolites: their use as therapeutic drugs, toxicological aspects, and analytical determination
J Gonçalves, T Rosado, S Soares, AY Simão… - Medicines, 2019 - mdpi.com
Although the medicinal properties of Cannabis species have been known for centuries, the
interest on its main active secondary metabolites as therapeutic alternatives for several …
interest on its main active secondary metabolites as therapeutic alternatives for several …
Pharmacological and therapeutic properties of cannabidiol for epilepsy
V Franco, E Perucca - Drugs, 2019 - Springer
Cannabidiol (CBD) is a major active component of the Cannabis plant, which, unlike
tetrahydrocannabinol (THC), is devoid of euphoria-inducing properties. During the last 10 …
tetrahydrocannabinol (THC), is devoid of euphoria-inducing properties. During the last 10 …
Safety, efficacy, and mechanisms of action of cannabinoids in neurological disorders
In the past two decades, there has been an increasing interest in the therapeutic potential of
cannabinoids for neurological disorders such as epilepsy, multiple sclerosis, pain, and …
cannabinoids for neurological disorders such as epilepsy, multiple sclerosis, pain, and …
Critical aspects affecting cannabidiol oral bioavailability and metabolic elimination, and related clinical implications
E Perucca, M Bialer - CNS drugs, 2020 - Springer
This article provides a critical appraisal of the available evidence concerning clinical
exposure to orally administered cannabidiol (CBD), with special reference to factors …
exposure to orally administered cannabidiol (CBD), with special reference to factors …
Emerging use of epidiolex (cannabidiol) in epilepsy
R Abu-Sawwa, B Scutt, Y Park - The Journal of Pediatric …, 2020 - meridian.allenpress.com
The first plant-derived, purified pharmaceutical-grade cannabidiol (CBD) medication,
Epidiolex, was approved in the United States by the FDA on June 25, 2018. Its approval for …
Epidiolex, was approved in the United States by the FDA on June 25, 2018. Its approval for …
Cannabis sativa: Much more beyond Δ9-tetrahydrocannabinol
P Alves, C Amaral, N Teixeira… - Pharmacological …, 2020 - Elsevier
Cannabis is the most used illicit drug worldwide and its medicinal use is under discussion,
being regulated in several countries. However, the psychotropic effects of Δ 9 …
being regulated in several countries. However, the psychotropic effects of Δ 9 …