Is H3K4me3 instructive for transcription activation?
Tri‐methylation of lysine 4 on histone H3 (H3K4me3) is a near‐universal chromatin
modification at the transcription start site of active genes in eukaryotes from yeast to man …
modification at the transcription start site of active genes in eukaryotes from yeast to man …
Chemically induced dimerization: reversible and spatiotemporal control of protein function in cells
S Voß, L Klewer, YW Wu - Current opinion in chemical biology, 2015 - Elsevier
Highlights•Novel orthogonal and reversible CID systems confer multiple layers of
manipulation.•Caged dimerizers allow control of protein function with spatiotemporal …
manipulation.•Caged dimerizers allow control of protein function with spatiotemporal …
COOLAIR and PRC2 function in parallel to silence FLC during vernalization
Noncoding transcription induces chromatin changes that can mediate environmental
responsiveness, but the causes and consequences of these mechanisms are still unclear …
responsiveness, but the causes and consequences of these mechanisms are still unclear …
Transcriptional neighborhoods regulate transcript isoform lengths and expression levels
Sequence features of genes and their flanking regulatory regions are determinants of RNA
transcript isoform expression and have been used as context-independent plug-and-play …
transcript isoform expression and have been used as context-independent plug-and-play …
Single-molecule imaging reveals a switch between spurious and functional ncRNA transcription
Eukaryotic transcription is pervasive, and many of the resulting RNAs are non-coding. It is
unknown whether ubiquitous transcription is functional or simply reflects stochastic …
unknown whether ubiquitous transcription is functional or simply reflects stochastic …
Biodegradation of phenol by Candida tropicalis sp.: Kinetics, identification of putative genes and reconstruction of catabolic pathways by genomic and transcriptomic …
Y He, Z Wang, T Li, X Peng, Y Tang, X Jia - Chemosphere, 2022 - Elsevier
Candida tropicalis sp. was isolated with predominant biodegradation capability to phenol
compounds, even with high concentration or in acid environment. The biodegradation of …
compounds, even with high concentration or in acid environment. The biodegradation of …
Intragenic enhancers attenuate host gene expression
Eukaryotic gene transcription is regulated at many steps, including RNA polymerase II (Pol
II) recruitment, transcription initiation, promoter-proximal Pol II pause release, and …
II) recruitment, transcription initiation, promoter-proximal Pol II pause release, and …
Modulation of mRNA and lncRNA expression dynamics by the Set2–Rpd3S pathway
H3K36 methylation by Set2 targets Rpd3S histone deacetylase to transcribed regions of
mRNA genes, repressing internal cryptic promoters and slowing elongation. Here we …
mRNA genes, repressing internal cryptic promoters and slowing elongation. Here we …
Selective suppression of antisense transcription by Set2-mediated H3K36 methylation
Maintenance of a regular chromatin structure over the coding regions of genes occurs co-
transcriptionally via the 'chromatin resetting'pathway. One of the central players in this …
transcriptionally via the 'chromatin resetting'pathway. One of the central players in this …
Paf1 has distinct roles in transcription elongation and differential transcript fate
RNA polymerase II (Pol2) movement through chromatin and the co-transcriptional
processing and fate of nascent transcripts is coordinated by transcription elongation factors …
processing and fate of nascent transcripts is coordinated by transcription elongation factors …