The approval of the first immune checkpoint inhibitors provided a paradigm shift for the
treatment of malignancies across a broad range of indications. Whereas initially, single …

Dendritic cells (DCs), a class of professional antigen-presenting cells, are considered key
factors in the initiation and maintenance of anti-tumor immunity due to their powerful ability …

Cancer incidence and mortality rates are increasing annually. Treatment with surgery,
chemotherapy and radiation therapy (RT) is unsatisfactory because many patients have …

Malignant melanoma is the leading cause of death among cutaneous malignancies. While
its incidence is increasing, the most recent cancer statistics show a small but clear decrease …

The clinical management of bladder cancer continues to present significant challenges.
Bacillus Calmette–Guérin (BCG) immunotherapy remains the gold standard of treatment for …

Dendritic cells (DCs) are asserted as the most potent antigen-presenting cells (APCs) that
orchestrate both innate and adaptive immunity, being extremely effective in the induction of …

Dendritic cells (DCs) are a heterogenous population of professional antigen presenting cells
whose main role is diminished in a variety of malignancies, including cancer, leading to …

Energy metabolism reprogramming is the characteristic feature of tumors. The
tumorigenesis, metastasis, and drug resistance of ovarian cancer (OC) is dependent on …

Background Tertiary lymphoid structures (TLSs) are potential prognostic indicators.
Radiomics may help reduce unnecessary invasive operations. Purpose To analyze the …

Colorectal cancer (CRC) remains a leading cause of cancer-related mortality despite efforts
to improve standard interventions. As CRC patients can benefit from immunotherapeutic …