[HTML][HTML] Mechanisms and applications of the regenerative capacity of platelets-based therapy in knee osteoarthritis

JY Zhang, XN **ang, X Yu, Y Liu, HY Jiang… - Biomedicine & …, 2024 - Elsevier
Osteoarthritis (OA) is the most prevalent joint disease in the elderly population and its
substantial morbidity and disability impose a heavy economic burden on patients and …

Research progress in decellularized extracellular matrix hydrogels for intervertebral disc degeneration

B Peng, L Du, T Zhang, J Chen, B Xu - Biomaterials science, 2023 - pubs.rsc.org
As one of the most common clinical disorders, low back pain (LBP) influences patient quality
of life and causes substantial social and economic burdens. Many factors can result in LBP …

Application of platelet-rich plasma in spinal surgery

H Wang, J Zhu, Y **a, Y Li, C Fu - Frontiers in endocrinology, 2023 - frontiersin.org
With the aging of the population and changes in lifestyle, the incidence of spine-related
diseases is increasing, which has become a major global public health problem; this results …

Local drug delivery challenges and innovations in spinal neurosurgery

C Karavasili, T Young, J Francis, J Blanco… - Journal of Controlled …, 2024 - Elsevier
The development of novel therapeutics in the field of spinal neurosurgery faces a litany of
translational challenges. Achieving precise drug targeting within the confined spaces …

lncRNA LINC00284 promotes nucleus pulposus cell proliferation and ECM synthesis via regulation of the miR-205-3p/Wnt/β-catenin axis

M Zhu, X Yan, Y Zhao, H Xue… - Molecular …, 2022 - spandidos-publications.com
Intervertebral disc degeneration (IDD) is a leading cause of degenerative spinal disease.
Long non-coding RNA (lncRNA) LINC00284 is overexpressed in multiple types of cancer …

[HTML][HTML] Regenerative potential of mouse neonatal intervertebral disc depends on collagen crosslink density

DN D'Erminio, KA Adelzadeh, AM Rosenberg… - Iscience, 2024 - cell.com
Intervertebral disc (IVD) defects heal poorly and can cause back pain and disability. We
identified that IVD herniation injury heals regeneratively in neonatal mice until postnatal day …

Occupational therapy‐based rehabilitation of sciatic nerve pain

S Thakur, A Kumar, A Dijkstra, A Thakur - Brain‐X, 2024 - Wiley Online Library
Sciatica is a severe form of pain caused by compression of the sciatic nerve that radiates
from the back toward the hip and outer side of the leg. Conventional treatments for sciatica …

Nucleus Disc Replacement: Design and Material Selection FEA Analysis

A Vanaclocha, V Vanaclocha… - … in Materials Science …, 2022 - Wiley Online Library
Study Design. We selected the materials and implant design and performed Finite Element
Analysis (FEA) studies. Background. Nucleus disc replacements, implanted since 1960 …

Bibliographic review of the efficacy of platelet-rich plasma treatment in lumbar disc herniation

AL Guerrero-Molina, MG Cruz-Álvarez… - Acta ortopédica …, 2023 - scielo.org.mx
Resumen GUERRERO-MOLINA, AL; CRUZ-ALVAREZ, MG y TENOPALA-VILLEGAS, S.
Bibliographic review of the efficacy of platelet-rich plasma treatment in lumbar disc …

[HTML][HTML] Revisión bibliográfica de la eficacia del tratamiento con plasma rico en plaquetas en hernia de disco lumbar

AL Guerrero-Molina, MG Cruz-Álvarez… - Acta ortopédica …, 2023 - scielo.org.mx
El plasma rico en plaquetas (PRP) es un producto sanguíneo autólogo que contiene
factores de crecimiento y proteínas y se ha utilizado en todo el entorno clínico para la …