For many years people have speculated that electroencephalographic activity or other
electrophysiological measures of brain function might provide a new non-muscular channel …

Most of our knowledge about the functional organization of neuronal systems is based on
the analysis of the firing patterns of individual neurons that have been recorded one by one …

Brain-machine interfaces (BMIs) combine methods, approaches, and concepts derived from
neurophysiology, computer science, and engineering in an effort to establish real-time …

Signals derived from the rat motor cortex can be used for controlling one-dimensional
movements of a robot arm. It remains unknown, however, whether real-time processing of …

To determine whether simultaneously recorded motor cortex neurons can be used for real-
time device control, rats were trained to position a robot arm to obtain water by pressing a …

I think, therefore I am. The legendary pronouncement of philosopher René Descartes lingers
as accepted wisdom in the Western world nearly four centuries after its author's death. But …

A paradigm is described for recording the activity of single cortical neurons from awake,
behaving macaque monkeys. Its unique features include high-density microwire arrays and …

Recent development of neural prosthetics for assisting paralyzed patients has focused on
decoding intended hand trajectories from motor cortical neurons and using this signal to …

Real-time direct interfaces between the brain and electronic and mechanical devices could
one day be used to restore sensory and motor functions lost through injury or disease …

The neural circuits underlying initial sensory processing of somatic information are relatively
well understood. In contrast, the processes that go beyond primary somatosensation to …