Intestinal mucus and their glycans: A habitat for thriving microbiota

AS Luis, GC Hansson - Cell Host & Microbe, 2023 - cell.com
The colon mucus layer is organized with an inner colon mucus layer that is impenetrable to
bacteria and an outer mucus layer that is expanded to allow microbiota colonization. A major …

Bacterial outer membrane vesicles: from discovery to applications

MG Sartorio, EJ Pardue, MF Feldman… - Annual review of …, 2021 - annualreviews.org
Secretion of cellular components across the plasma membrane is an essential process that
enables organisms to interact with their environments. Production of extracellular vesicles in …

Versatility of bacterial outer membrane vesicles in regulating intestinal homeostasis

X Wang, S Lin, L Wang, Z Cao, M Zhang, Y Zhang… - Science …, 2023 - science.org
Outer membrane vesicles (OMVs) play vital roles in bacterial communication both
intraspecifically and interspecifically. However, extracellular mechanisms of gut microbiota …

Microbiota‐derived extracellular vesicles in interkingdom communication in the gut

N Díaz‐Garrido, J Badia… - Journal of Extracellular …, 2021 - Wiley Online Library
The intestine is fundamental in controlling human health. Intestinal epithelial and immune
cells are continuously exposed to millions of microbes that greatly impact on intestinal …

[HTML][HTML] Bacterial extracellular vesicles as bioactive nanocarriers for drug delivery: Advances and perspectives

H Liu, Q Zhang, S Wang, W Weng, Y **g, J Su - Bioactive materials, 2022 - Elsevier
Nanosized extracellular vesicles derived from bacteria contain diverse cargo and transfer
intercellular bioactive molecules to cells. Due to their favorable intercellular interactions, cell …

A single sulfatase is required to access colonic mucin by a gut bacterium

AS Luis, C **, GV Pereira, RWP Glowacki, SR Gugel… - Nature, 2021 - nature.com
Humans have co-evolved with a dense community of microbial symbionts that inhabit the
lower intestine. In the colon, secreted mucus creates a barrier that separates these …

Gut microbiome, metabolome, host immunity associated with inflammatory bowel disease and intervention of fecal microbiota transplantation

R Wu, R **ong, Y Li, J Chen, R Yan - Journal of autoimmunity, 2023 - Elsevier
Gut dysbiosis has been associated with inflammatory bowel disease (IBD), one of the most
common gastrointestinal diseases. The microbial communities play essential roles in host …

A dietary fiber-deprived gut microbiota degrades the colonic mucus barrier and enhances pathogen susceptibility

MS Desai, AM Seekatz, NM Koropatkin, N Kamada… - Cell, 2016 - cell.com
Despite the accepted health benefits of consuming dietary fiber, little is known about the
mechanisms by which fiber deprivation impacts the gut microbiota and alters disease risk …

Extracellular membrane vesicles in the three domains of life and beyond

S Gill, R Catchpole, P Forterre - FEMS microbiology reviews, 2019 - academic.oup.com
Cells from all three domains of life, Archaea, Bacteria and Eukarya, produce extracellular
vesicles (EVs) which are sometimes associated with filamentous structures known as …

Gastrointestinal biofilms in health and disease

JP Motta, JL Wallace, AG Buret, C Deraison… - Nature Reviews …, 2021 - nature.com
Microorganisms colonize various ecological niches in the human habitat, as they do in
nature. Predominant forms of multicellular communities called biofilms colonize human …