Turnitin
降AI改写
早检测系统
早降重系统
Turnitin-UK版
万方检测-期刊版
维普编辑部版
Grammarly检测
Paperpass检测
checkpass检测
PaperYY检测
Comprehensive review in current developments of imidazole‐based medicinal chemistry
L Zhang, XM Peng, GLV Damu… - Medicinal research …, 2014 - Wiley Online Library
Imidazole ring is an important five‐membered aromatic heterocycle widely present in natural
products and synthetic molecules. The unique structural feature of imidazole ring with …
products and synthetic molecules. The unique structural feature of imidazole ring with …
On various metrics used for validation of predictive QSAR models with applications in virtual screening and focused library design
K Roy, I Mitra - Combinatorial chemistry & high throughput …, 2011 - ingentaconnect.com
Quantitative structure-activity relationships (QSARs) have important applications in drug
discovery research, environmental fate modeling, property prediction, etc. Validation has …
discovery research, environmental fate modeling, property prediction, etc. Validation has …
Further exploring rm2 metrics for validation of QSPR models
Quantitative structure–property relationship (QSPR) models are widely used for prediction of
properties, activities and/or toxicities of new chemicals. Validation strategies check the …
properties, activities and/or toxicities of new chemicals. Validation strategies check the …
On further application of r as a metric for validation of QSAR models
Validation is a crucial aspect for quantitative structure–activity relationship (QSAR) model
development. External validation is considered, in general, as the most conclusive proof of …
development. External validation is considered, in general, as the most conclusive proof of …
On the use of the metric rm 2 as an effective tool for validation of QSAR models in computational drug design and predictive toxicology
K Roy, I Mitra - Mini Reviews in Medicinal Chemistry, 2012 - ingentaconnect.com
Validation of quantitative structure-activity relationship (QSAR) models plays a key role for
the selection of robust and predictive models that may be employed for further activity …
the selection of robust and predictive models that may be employed for further activity …
Pharmacophore filtering and 3D-QSAR in the discovery of new JAK2 inhibitors
Janus kinase 2 (JAK2) plays a crucial role in the patho-mechanism of cardiovascular
pathologies, myeloproliferative disorders and many other diseases. Thus, effective JAK2 …
pathologies, myeloproliferative disorders and many other diseases. Thus, effective JAK2 …
How to judge predictive quality of classification and regression based QSAR models?
K Roy, S Kar - Frontiers in computational chemistry, 2015 - Elsevier
Quantitative structure-activity relationship (QSAR) is a statistical modelling approach that
can be used in drug discovery, environmental fate modeling, property and activity prediction …
can be used in drug discovery, environmental fate modeling, property and activity prediction …
Molecular modeling studies on imidazo [4, 5-b] pyridine derivatives as Aurora A kinase inhibitors using 3D-QSAR and docking approaches
P Lan, WN Chen, WM Chen - European journal of medicinal chemistry, 2011 - Elsevier
3D-QSAR and docking studies were performed on sixty imidazo [4, 5-b] pyridine derivatives
as Aurora A kinase inhibitors. The CoMFA and CoMSIA models using forthy-eight molecules …
as Aurora A kinase inhibitors. The CoMFA and CoMSIA models using forthy-eight molecules …
2-Butyl-4-chloroimidazole based substituted piperazine-thiosemicarbazone hybrids as potent inhibitors of Mycobacterium tuberculosis
Here a series of 2-butyl-4-chloroimidazole based substituted piperazine-thiosemicarbazone
hybrids were designed by combining three different pharmacophoric fragments in single …
hybrids were designed by combining three different pharmacophoric fragments in single …
Imidazole and its derivatives as potential candidates for drug development
Imidazole and its derivatives are the pharmacological significant scaffolds with the broad
spectrum of activities can be synthesized in the laboratory in the single step by the action of …
spectrum of activities can be synthesized in the laboratory in the single step by the action of …