Fibrin clot properties in cardiovascular disease: from basic mechanisms to clinical practice

M Ząbczyk, RAS Ariëns, A Undas - Cardiovascular research, 2023 - academic.oup.com
Fibrinogen conversion into insoluble fibrin and the formation of a stable clot is the final step
of the coagulation cascade. Fibrin clot porosity and its susceptibility to plasmin-mediated …

Fibrinogen and fibrin: synthesis, structure, and function in health and disease

AS Wolberg - Journal of Thrombosis and Haemostasis, 2023 - Elsevier
Fibrinogen is an extraordinary molecule by any estimation. It is large, structurally intricate,
and circulates at high concentrations. Its biological end product, insoluble fibrin (ogen) or …

Deconstructing fibrin (ogen) structure

RA Risman, M Sen, V Tutwiler, NE Hudson - Journal of Thrombosis and …, 2024 - Elsevier
Fibrinogen and its insoluble degradation product fibrin are pivotal plasma proteins that play
important roles in blood coagulation, wound healing, and immune responses. This review …

[HTML][HTML] Fungi Fibrinolytic Compound 1 Plays a Core Role in Modulating Fibrinolysis, Altering Plasma Clot Structure, and Promoting Susceptibility to Lysis

C Gao, B Bao, C Bao, W Wu - Pharmaceutics, 2023 - mdpi.com
Fibrin clot structure and function are major determinants of venous and arterial
thromboembolic diseases, as well as the key determinants of the efficiency of clot lysis …

[HTML][HTML] Rupture mechanics of blood clots: Influence of fibrin network structure on the rupture resistance

RK Ramanujam, F Maksudov, RA Risman, RI Litvinov… - Acta Biomaterialia, 2024 - Elsevier
Embolization is a leading cause of mortality, yet we know little about clot rupture mechanics.
Fibrin provides the main structural and mechanical stability to blood clots. Previous studies …

In-vitro fibrin assembly: From the bulk to the interface

J Wu, T Ngai - Current Opinion in Colloid & Interface Science, 2023 - Elsevier
The assembly of fibrinogen to a fibrin network has great implications not only for
physiological processes, like hemostasis and wound healing, but also for the inspiration of …

O PAPEL DO FIBRINOGÊNIO E SEU ENVOLVIMENTO NAS DOENÇAS CARDIOVASCULARES

ABM de Vasconcellos, A de Oliveira Mendes… - Epitaya E …, 2024 - portal.epitaya.com.br
O fibrinogênio é uma proteína plasmática crucial na cascata de coagulação sanguínea,
desempenhando um papel fundamental na formação de coágulos. No contexto das …