Glutamate dehydrogenase (GDH) is a hexameric enzyme that catalyzes the reversible
conversion of glutamate to α-ketoglutarate and ammonia while reducing NAD (P)+ to NAD …

Free ammonium ions are produced and consumed during cell metabolism. Glutamine
synthetase utilizes free ammonium ions to produce glutamine in the cytosol whereas …

Photocatalytic overall water splitting is an environmentally friendly technique for hydrogen
(H 2) and oxygen (O 2) production. Here, we report an in situ growth strategy for …

The nicotinamide adenine dinucleotide (NAD+/NADH) and nicotinamide adenine
dinucleotide phosphate (NADP+/NADPH) redox couples function as cofactors or/and …

Nicotinamide phosphoribosyltransferase (NAMPT) catalyzes the first rate-limiting step in
converting nicotinamide to NAD+, essential for cellular metabolism, energy production, and …

Metabolism has recently emerged as a major target of genes implicated in the evolutionary
expansion of human neocortex. One such gene is the human-specific gene ARHGAP11B …

The origination of new genes contributes to phenotypic evolution in humans. Two major
challenges in the study of new genes are the inference of gene ages and annotation of their …

“What makes us human?” is a central question of many research fields, notably
anthropology. In this review, we focus on the development of the human neocortex, the part …

A facilitative transport system exists on the blood–brain barrier (BBB) that has been tacitly
assumed to be a path for glutamate entry to the brain. However, glutamate is a non-essential …

Glutamate dehydrogenase (GDH) catalyzes the reversible inter-conversion of glutamate to α-
ketoglutarate and ammonia. High levels of GDH activity is found in mammalian liver, kidney …