As a substantial part of the brain tumor microenvironment (TME), glioma-associated
microglia/macrophages (GAMs) have an emerging role in tumor progression and in …

Proper development and function of the mammalian central nervous system (CNS) depend
critically on the activity of parenchymal sentinels referred to as microglia. Although microglia …

It is well established that microglial form and function are inextricably linked. In recent years,
the traditional view that microglial form ranges between “ramified resting” and “activated …

Microglia, the primary resident immune cells of the central nervous system (CNS), exhibit
dynamic behavior involving rapid process motility and cellular migration that is thought to …

The current study, in parallel experiments, evaluated the impact of chronic psychological
stress on physiological and behavioural measures, and on the activation status of microglia …

The dynamics of microglial cell activation was studied in freshly prepared rat brain tissue
slices. Microglia became activated in the tissue slices, as evidenced by their conversion from …

Chronic stress can alter the immune system, adult hippocampal neurogenesis and induce
anxiety-and depressive-like behaviour in rodents. However, previous studies have not …

A century after Cajal identified a “third element” of the nervous system, many issues have
been clarified about the identity and function of one of its major components, the microglia …

Tumor necrosis factor α (TNF) mediates homeostatic synaptic plasticity (HSP) in response to
chronic activity blockade, and prior work has established that it is released from glia. Here …

Little is known about microglial activation and macrophage localization after diffuse brain
injury (DBI). DBI-mediated perisomatic traumatic axonal injury (TAI) was recently identified …