Role of salivary biomarkers in oral cancer detection

Z Khurshid, MS Zafar, RS Khan, S Najeeb… - Advances in clinical …, 2018‏ - Elsevier
Oral cancers are the sixth most frequent cancer with a high mortality rate. Oral squamous
cell carcinoma accounts for more than 90% of all oral cancers. Standard methods used to …

Glycosylation: a hallmark of cancer?

BN Vajaria, PS Patel - Glycoconjugate journal, 2017‏ - Springer
The hallmarks of cancer are characterized by functional capabilities that allow cancer cells
to survive, proliferate and disseminate during the multistep tumorigenesis. Cancer being a …

A review of research on salivary biomarkers for oral cancer detection

YSL Cheng, T Rees, J Wright - Clinical and translational medicine, 2014‏ - Springer
Using saliva for disease diagnostics and health surveillance is a promising approach as
collecting saliva is relatively easy and non-invasive. Over the past two decades, using …

Serum sialylation changes in cancer

Z Zhang, M Wuhrer, S Holst - Glycoconjugate journal, 2018‏ - Springer
Cancer is a major cause of death in both develo** and developed countries. Early
detection and efficient therapy can greatly enhance survival. Aberrant glycosylation has …

Evaluation of saliva and plasma cytokine biomarkers in patients with oral squamous cell carcinoma

LT Lee, YK Wong, HY Hsiao, YW Wang… - International Journal of …, 2018‏ - Elsevier
The aim of this study was to investigate potential biomarkers in human saliva and plasma to
aid in the early diagnosis of oral squamous cell carcinoma (OSCC). Saliva and plasma …

Salivary biomarkers for detection of oral squamous cell carcinoma: current state and recent advances

M Yakob, L Fuentes, MB Wang, E Abemayor… - Current oral health …, 2014‏ - Springer
Oral squamous cell carcinoma (OSCC) is the most common malignant neoplasm of the oral
cavity. Detection of OSCC is currently based on a thorough clinical oral examination …

Sha** the future of oral cancer diagnosis: advances in salivary proteomics

O Barros, VG D'Agostino, L Lara Santos… - Expert Review of …, 2024‏ - Taylor & Francis
Introduction Saliva has gained increasing attention in the quest for disease biomarkers.
Because it is a biological fluid that can be collected is an easy, painless, and safe way, it has …

Validation of salivary markers, IL-1β, IL-8 and Lgals3bp for detection of oral squamous cell carcinoma in an Indian population

P Singh, JK Verma, JK Singh - Scientific reports, 2020‏ - nature.com
Early detection and easier follow-up of oral squamous cell carcinoma (OSCC) would
significantly improve the morbidity and mortality associated with it. With newer technologies …

Past, present, and future diagnostic methods for the early noninvasive detection of oral premalignant lesions: a state of the art and systematic review

B Khong, S Ferlito, S Quek, G Conte… - Ear, Nose & Throat …, 2024‏ - journals.sagepub.com
Objectives: To provide an in-depth analysis of noninvasive methods for the early diagnosis
of oral premalignant lesions, focusing on novel biomarkers and optical technologies, and to …

A literature review of the potential diagnostic biomarkers of head and neck neoplasms

H Konings, S Stappers, M Geens, BY De Winter… - Frontiers in …, 2020‏ - frontiersin.org
Head and neck neoplasms have a poor prognosis because of their late diagnosis. Finding a
biomarker to detect these tumors in an early phase could improve the prognosis and survival …