Pushing Boundaries: What's Next in Metal-Free C–H Functionalization for Sulfenylation?

P Rani, S Chahal, R Singh, J Sindhu - Topics in Current Chemistry, 2024 - Springer
The synthesis of thioether derivatives has been explored widely due to the potential
application of these derivatives in medicinal chemistry, pharmaceutical industry and material …

Rationally designed novel phenazine based chemosensor with real time Hg2+ sensing application

P Rani, S Chahal, R Singh, S Kumar, P Kumar… - Journal of Molecular …, 2023 - Elsevier
Phenazine derivatives have been explored in the selective detection of ions due to their
binding ability with analytes. In this context, C-6 sulfenylated benzo [a] phenazine-5-ols (3a …

Rationally designed C-3 sulfenylated 2-phenyl-4H-pyrido [1, 2-a] pyrimidin-4-one based fluorescent probe for recognition of Fe3+

P Rani, R Kataria, P Kumar, D Singh, A Duhan… - Journal of Molecular …, 2024 - Elsevier
Cross-dehydrogenative coupling (CDC) efficiently constructs complex organic molecules by
directly coupling two CH bonds from different substrates. This enables the functionalisation …

Metal-free CH thioarylation of uracils and in situ generated enaminones using thiols in the presence of hexachloroethane

A Arman, N Nowrouzi, M Abbasi - Tetrahedron Letters, 2024 - Elsevier
A metal-free and one-pot procedure for thioarylation of uracils and in situ generated
enaminones with thiols in the presence of C 2 Cl 6 is introduced. This protocol is a less toxic …

Design and Development of Novel Hybrids Based on Pyrrolo[2,1‐f][1,2,4]Triazine and 1‐(Methylpiperidin‐4‐yl) Aniline–Based Analogs: Exploring the Utility as …

BD Sathe, S Jaiswal, D Kumar, TG Singh… - Chemical Biology & …, 2024 - Wiley Online Library
ABSTRACT Mer‐tyrosine kinase (MERTK), a member of the AXL, TYRO3, and MERTK
(TAM) family, is one of the promising targets for cancer treatment. It plays a key role in …

Utility of Some New Pyrimidine Thiol Derivatives: Computational study of Molecular Docking and Biological Activity observation

NH Ibrahim, EM Kamel, MA Hosny… - Egyptian Journal of …, 2024 - ejchem.journals.ekb.eg
A new series of 5-8 and 10 & 11 was prepared based on 4-(4-chlorophenyl)-2-mercapto-6-
oxo-1, 6-dihydropyrimidine-5-carbonitrile 4 and 4-(4-chlorophenyl)-2-hydrazinyl-6-oxo-1, 6 …

Development of New N-{4-[(7-Chloro-5-methylpyrrolo [2, 1-f][1, 2, 4] triazin-4-yl) oxy]-3-fluorophenyl} benzenesulfonamide Analogues: Exploring Anticancer Potential …

BD Sathe, M Meenakshi, Y Murti, MS Mane… - Synlett, 2024 - thieme-connect.com
Mer proto-oncogene tyrosine-protein kinase (MerTK), a part of the TAM (TYRO3, AXL, and
MerTK) family, is directly correlated with metastasis and various types of cancers. The …

[HTML][HTML] Molecular Docking/ADME-TOX-Based Analysis for New Anti-Colorectal Cancer Through Peroxiredoxin 1 Inhibition

I Bensahbane, N Melkemi, I Daoud, F Asli - Chemistry Proceedings, 2024 - mdpi.com
Colorectal cancer ranks as the third most prevalent form of cancer on a global scale. The
abnormal expression of Peroxiredoxin 1, or PRDX1, plays an important role in cancer …

[PDF][PDF] PRDX1 Inhibition Based on Molecular Docking and ADME-TOX Study Using New Anti-Colorectal Cancer Compounds

I Bensahbane, N Melkemi, I Daoud, F Asli - Chem. Proc, 2024 - sciforum.net
Colorectal cancer ranks as the third most prevalent form of cancer on a global scale. The
abnormal expression of Peroxiredoxin 1, or PRDX1, plays an important role in cancer …