Mechanical properties of whole-body soft human tissues: a review

G Singh, A Chanda - Biomedical Materials, 2021 - iopscience.iop.org
The mechanical properties of soft tissues play a key role in studying human injuries and their
mitigation strategies. While such properties are indispensable for computational modelling …

Fifty shades of brain: a review on the mechanical testing and modeling of brain tissue

S Budday, TC Ovaert, GA Holzapfel… - … Methods in Engineering, 2020 - Springer
Brain tissue is not only one of the most important but also the most complex and compliant
tissue in the human body. While long underestimated, increasing evidence confirms that …

Mechanical characterization of human brain tissue

S Budday, G Sommer, C Birkl, C Langkammer… - Acta biomaterialia, 2017 - Elsevier
Mechanics are increasingly recognized to play an important role in modulating brain form
and function. Computational simulations are a powerful tool to predict the mechanical …

Automated model discovery for human brain using constitutive artificial neural networks

K Linka, SRS Pierre, E Kuhl - Acta Biomaterialia, 2023 - Elsevier
The brain is our softest and most vulnerable organ, and understanding its physics is a
challenging but significant task. Throughout the past decade, numerous competing models …

An introduction to the Ogden model in biomechanics: benefits, implementation tools and limitations

MJ Lohr, GP Sugerman… - … of the Royal …, 2022 - royalsocietypublishing.org
Constitutive models are important to biomechanics for two key reasons. First, constitutive
modelling is an essential component of characterizing tissues' mechanical properties for …

Mechanics of the brain: perspectives, challenges, and opportunities

A Goriely, MGD Geers, GA Holzapfel… - … and modeling in …, 2015 - Springer
The human brain is the continuous subject of extensive investigation aimed at
understanding its behavior and function. Despite a clear evidence that mechanical factors …

How to characterize a nonlinear elastic material? A review on nonlinear constitutive parameters in isotropic finite elasticity

LA Mihai, A Goriely - Proceedings of the Royal Society A …, 2017 - royalsocietypublishing.org
The mechanical response of a homogeneous isotropic linearly elastic material can be fully
characterized by two physical constants, the Young's modulus and the Poisson's ratio, which …

Self-assembling hydrogel structures for neural tissue repair

S Peressotti, GE Koehl, JA Goding… - … Biomaterials Science & …, 2021 - ACS Publications
Hydrogel materials have been employed as biological scaffolds for tissue regeneration
across a wide range of applications. Their versatility and biomimetic properties make them …

Rheological characterization of human brain tissue

S Budday, G Sommer, J Haybaeck, P Steinmann… - Acta biomaterialia, 2017 - Elsevier
The rheology of ultrasoft materials like the human brain is highly sensitive to regional and
temporal variations and to the type of loading. While recent experiments have shaped our …

[HTML][HTML] A family of hyperelastic models for human brain tissue

LA Mihai, S Budday, GA Holzapfel, E Kuhl… - Journal of the Mechanics …, 2017 - Elsevier
Experiments on brain samples under multiaxial loading have shown that human brain tissue
is both extremely soft when compared to other biological tissues and characterized by a …