Ionic liquids: new forms of active pharmaceutical ingredients with unique, tunable properties

JL Shamshina, RD Rogers - Chemical Reviews, 2023 - ACS Publications
This Review aims to summarize advances over the last 15 years in the development of
active pharmaceutical ingredient ionic liquids (API-ILs), which make up a prospective game …

Recent advances in ionic liquids in biomedicine

AM Curreri, S Mitragotri, EEL Tanner - Advanced Science, 2021 - Wiley Online Library
The use of ionic liquids and deep eutectic solvents in biomedical applications has grown
dramatically in recent years due to their unique properties and their inherent tunability. This …

Permeation enhancers in transdermal drug delivery: Benefits and limitations

A Kováčik, M Kopečná, K Vávrová - Expert opinion on drug delivery, 2020 - Taylor & Francis
Introduction: Transdermal drug delivery has several clinical benefits over conventional
routes of drug administration. To open the transdermal route for a wider range of drugs …

Development of ionic liquid-coated PLGA nanoparticles for applications in intravenous drug delivery

CM Hamadani, GS Dasanayake, ME Gorniak… - Nature …, 2023 - nature.com
Polymeric nanoparticles (NPs) are a promising platform for medical applications in drug
delivery. However, their use as drug carriers is limited by biological (eg, immunological) …

Biocompatible ionic liquids and their applications in pharmaceutics

RM Moshikur, MR Chowdhury, M Moniruzzaman… - Green …, 2020 - pubs.rsc.org
Ionic liquids (ILs) have been used as solvents or materials, or both, in many applications,
including pharmaceutics and medicine due to their exceptional properties consisting of the …

The role of ionic liquids in the pharmaceutical field: An overview of relevant applications

SN Pedro, CS R. Freire, AJD Silvestre… - International journal of …, 2020 - mdpi.com
Solubility, bioavailability, permeation, polymorphism, and stability concerns associated to
solid-state pharmaceuticals demand for effective solutions. To overcome some of these …

Progress in natural polymer engineered biomaterials for transdermal drug delivery systems

VS Sivasankarapillai, SS Das, F Sabir… - Materials Today …, 2021 - Elsevier
The route of a specific drug carrier system is always a significant platform of development
that combines the principles of biomedical technology, nanotechnology, and pharmaceutical …

Ionic liquid‐based stimuli‐responsive functional materials

J Cui, Y Li, D Chen, TG Zhan… - Advanced Functional …, 2020 - Wiley Online Library
Ionic liquids (ILs) have many attractive properties. For example, their physical and chemical
properties can be tuned by a judicious design of the cations and anions, making them ideal …

Mechanisms of action of ionic liquids on living cells: The state of the art

P Kumari, VVS Pillai, A Benedetto - Biophysical reviews, 2020 - Springer
Ionic liquids (ILs) are a relatively new class of organic electrolytes composed of an organic
cation and either an organic or inorganic anion, whose melting temperature falls around …

Ionic liquids as a useful tool for tailoring active pharmaceutical ingredients

X Wu, Q Zhu, Z Chen, W Wu, Y Lu, J Qi - Journal of Controlled Release, 2021 - Elsevier
Ionic liquids (ILs) have been widely used in biomedical and pharmaceutical fields as
solvents or permeation enhancers. Recently, more and more researchers focused on …