The merits of continuous processing over batch processing are well known in the
manufacturing industry. Continuous operation results in shorter process times due to …

Continuous integrated bioprocessing has elicited considerable interest from the biopharma
industry for the many purported benefits it promises. Today many major biopharma …

Continuous production delivers higher productivity and better quality than traditional batch-
wise approaches. It intensifies production lowering capital cost and enables better control …

Continuous processing offers a promising approach to revolutionize biotherapeutics
manufacturing as reflected in recent years. The current study offers a comparative economic …

Narrow residence time distributions (RTDs) are desirable in many chemical engineering
processes. However, when a system operates in the laminar flow regime, significant fluid …

The present study focuses on the measurement of residence time distribution (RTD) in
coiled tubes and coiled flow inverters (CFI) over a wide range of Reynolds numbers (N Re) …

Abstract Model‐based design of integrated continuous train coupled with online process
analytical technology (PAT) tool can be a potent facilitator for monitoring and control of …

Abstract Coiled Flow Inverter Reactor (CFIR) has recently been explored for facilitating
continuous operation of several unit operations involved in downstream processing of …

Protein A capture chromatography, the core of a mAb purification platform, is known to
account for more than 50% of downstream processing costs along with other limitations …

Monoclonal antibody downstream processing typically entails chromatography-based
purification processes beginning with Protein A chromatography, accounting for 50% of the …