Present status of microfluidic PCR chip in nucleic acid detection and future perspective

S Chen, Y Sun, F Fan, S Chen, Y Zhang… - TrAC Trends in …, 2022 - Elsevier
Polymerase chain reaction (PCR) amplifies specific fragment of DNA molecules and has
been extensively applied in fields of pathogens and gene mutation detection, food safety …

Digital microfluidics for biological analysis and applications

X Xu, L Cai, S Liang, Q Zhang, S Lin, M Li, Q Yang… - Lab on a Chip, 2023 - pubs.rsc.org
Digital microfluidics (DMF) is an emerging liquid-handling technology based on arrays of
microelectrodes for the precise manipulation of discrete droplets. DMF offers the benefits of …

A review of digital microfluidics as portable platforms for lab-on a-chip applications

E Samiei, M Tabrizian, M Hoorfar - Lab on a Chip, 2016 - pubs.rsc.org
Following the development of microfluidic systems, there has been a high tendency towards
develo** lab-on-a-chip devices for biochemical applications. A great deal of effort has …

Digital microfluidics

K Choi, AHC Ng, R Fobel… - Annual review of …, 2012 - annualreviews.org
Digital microfluidics (DMF) is an emerging liquid-handling technology that enables
individual control over droplets on an open array of electrodes. These picoliter-to microliter …

Microfluidic lab-on-a-chip platforms: requirements, characteristics and applications

D Mark, S Haeberle, G Roth, F Von Stetten… - Microfluidics based …, 2010 - Springer
This review summarizes recent developments in microfluidic platform approaches. In
contrast to isolated application-specific solutions, a microfluidic platform provides a set of …

A novel electrophoretic assisted hydrophobic microdevice for enhancing blood cell sorting: design and numerical simulation

X Chen, X Chen - Analytical Methods, 2024 - pubs.rsc.org
Microfluidic technology has great advantages in the precise manipulation of micro–nano
particles, and the hybrid microfluidic separation technology has attracted much attention due …

Microfluidic designs and techniques using lab-on-a-chip devices for pathogen detection for point-of-care diagnostics

AM Foudeh, TF Didar, T Veres, M Tabrizian - Lab on a Chip, 2012 - pubs.rsc.org
Effective pathogen detection is an essential prerequisite for the prevention and treatment of
infectious diseases. Despite recent advances in biosensors, infectious diseases remain a …

Development of a digital microfluidic platform for point of care testing

R Sista, Z Hua, P Thwar, A Sudarsan, V Srinivasan… - Lab on a Chip, 2008 - pubs.rsc.org
Point of care testing is playing an increasingly important role in improving the clinical
outcome in health care management. The salient features of a point of care device are rapid …

Digital microfluidics: a versatile tool for applications in chemistry, biology and medicine

MJ Jebrail, MS Bartsch, KD Patel - Lab on a Chip, 2012 - pubs.rsc.org
Digital microfluidics (DMF) has recently emerged as a popular technology for a wide range
of applications. In DMF, nanoliter to microliter droplets containing samples and reagents can …

Miniaturized PCR chips for nucleic acid amplification and analysis: latest advances and future trends

C Zhang, D **ng - Nucleic acids research, 2007 - academic.oup.com
The possibility of performing fast and small-volume nucleic acid amplification and analysis
on a single chip has attracted great interest. Devices based on this idea, referred to as micro …