DExH/D-box helicases are essential nucleic acid and ribonucleoprotein remodelers
involved in all aspects of nucleic acid metabolism including replication, gene expression …

The hepatic complications of chronic hepatitis C (CHC) usually occur only after progression
to cirrhosis has taken place. Progression to cirrhosis, however, is extremely variable and …

ABSTRACT DDX3, a DEAD-box RNA helicase, binds to the hepatitis C virus (HCV) core
protein. However, the role (s) of DDX3 in HCV replication is still not understood. Here we …

The development of hepatocellular carcinoma (HCC) in persons who are persistently
infected with hepatitis C virus (HCV) is a growing problem worldwide. Current antiviral …

Dengue virus (DENV), an emerging mosquito-transmitted pathogen capable of causing
severe disease in humans, interacts with host cell factors to create a more favorable …

The DEAD-box RNA helicase DDX3 is a multifunctional protein involved in all aspects of
RNA metabolism, including transcription, splicing, mRNA nuclear export, translation, RNA …

The DEAD-box RNA helicase DDX5 is a member of a family of highly conserved proteins
involved in gene-expression regulation and ATP-dependent RNA helicase activities …

DExD/H-box helicase (DDX) 5 belongs to the DExD/H-box helicase family. DDX family
members play differential roles in the regulation of innate antiviral immune response …

DEAD-box helicases play essential roles in RNA metabolism across species, but emerging
data suggest that they have additional functions in immunity. Through RNAi screening, we …

RNA helicases are involved in almost every aspect of RNA, from transcription to RNA decay.
DExD/H-box helicases comprise the largest SF2 helicase superfamily, which are …