Enhancing permeation of drug molecules across the skin via delivery in nanocarriers: novel strategies for effective transdermal applications

YQ Yu, X Yang, XF Wu, YB Fan - Frontiers in bioengineering and …, 2021 - frontiersin.org
The transdermal route of administration provides numerous advantages over conventional
routes ie, oral or injectable for the treatment of different diseases and cosmetics applications …

Topical drug delivery: History, percutaneous absorption, and product development

MS Roberts, HS Cheruvu, SE Mangion… - Advanced drug delivery …, 2021 - Elsevier
Topical products, widely used to manage skin conditions, have evolved from simple potions
to sophisticated delivery systems. Their development has been facilitated by advances in …

Physicochemical and biopharmaceutical aspects influencing skin permeation and role of SLN and NLC for skin drug delivery

EB Souto, JF Fangueiro, AR Fernandes, A Cano… - Heliyon, 2022 - cell.com
The skin is a complex and multifunctional organ, in which the static versus dynamic balance
is responsible for its constant adaptation to variations in the external environment that is …

[HTML][HTML] Nanoemulsion: A review on mechanisms for the transdermal delivery of hydrophobic and hydrophilic drugs

DS Shaker, RAH Ishak, A Ghoneim… - Scientia Pharmaceutica, 2019 - mdpi.com
Nanoemulsions (NEs) are colloidal dispersions of two immiscible liquids, oil and water, in
which one is dispersed in the other with the aid of a surfactant/co-surfactant mixture, either …

SVOC exposure indoors: fresh look at dermal pathways

CJ Weschler, WW Nazaroff - Indoor air, 2012 - Wiley Online Library
This paper critically examines indoor exposure to semivolatile organic compounds (SVOCs)
via dermal pathways. First, it demonstrates that–in central tendency–an SVOC's abundance …

Nanotechnology and the transdermal route: A state of the art review and critical appraisal

G Cevc, U Vierl - Journal of controlled release, 2010 - Elsevier
The skin is refractive to most molecules, especially hydrophilic ones, despite the existence of
trans-barrier pathways. It is essential to maintain this protective barrier even after breaching …

Lipid vesicles and other colloids as drug carriers on the skin

G Cevc - Advanced drug delivery reviews, 2004 - Elsevier
Colloids from an aqueous suspension can cross the skin barrier only through hydrophilic
pathways. Various colloids have a different ability to do this by penetrating narrow pores of …

Mathematical models of skin permeability: an overview

S Mitragotri, YG Anissimov, AL Bunge… - International journal of …, 2011 - Elsevier
Mathematical models of skin permeability play an important role in various fields including
prediction of transdermal drug delivery and assessment of dermal exposure to industrial …

Potential of nanoparticulate carriers for improved drug delivery via skin

A Zeb, ST Arif, M Malik, FA Shah, FU Din… - Journal of …, 2019 - Springer
Skin as a delivery route for drugs has attracted a great attention in recent decades as it
avoids many of the limitations of oral and parenteral administration. However, the excellent …

Advancements in Skin‐Mediated Drug Delivery: Mechanisms, Techniques, and Applications

DH Lee, S Lim, SS Kwak, J Kim - Advanced Healthcare …, 2024 - Wiley Online Library
Skin‐mediated drug delivery methods currently are receiving significant attention as a
promising approach for the enhanced delivery of drugs through the skin. Skin‐mediated …