The role of microRNA-185 in the pathogenesis of human diseases: a focus on cancer
MicroRNAs (miRNAs) are a widely-studied class of non-coding RNAs characterized by their
short length (18-25 nucleotides). The precise functions of miRNAs are not well-elucidated; …
short length (18-25 nucleotides). The precise functions of miRNAs are not well-elucidated; …
Molecular genetics of adult acute myeloid leukemia: prognostic and therapeutic implications
Molecular analyses of leukemic blasts from patients with acute myeloid leukemia (AML)
have revealed a striking heterogeneity with regard to the presence of acquired gene …
have revealed a striking heterogeneity with regard to the presence of acquired gene …
Haemolysis during sample preparation alters microRNA content of plasma
The presence of cell-free microRNAs (miRNAs) has been detected in a range of body fluids.
The miRNA content of plasma/serum in particular has been proposed as a potential source …
The miRNA content of plasma/serum in particular has been proposed as a potential source …
MicroRNAs: new regulators of immune cell development and function
Decades of research went into understanding immune cell development and function
without awareness that consideration of a key element, microRNA (miRNA), was lacking …
without awareness that consideration of a key element, microRNA (miRNA), was lacking …
miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells
Background Glioblastoma multiforme (GBM) is an invariably fatal central nervous system
tumor despite treatment with surgery, radiation, and chemotherapy. Further insights into the …
tumor despite treatment with surgery, radiation, and chemotherapy. Further insights into the …
Normalization of microRNA expression levels in quantitative RT-PCR assays: identification of suitable reference RNA targets in normal and cancerous human solid …
HJ Peltier, GJ Latham - Rna, 2008 - rnajournal.cshlp.org
Proper normalization is a critical but often an underappreciated aspect of quantitative gene
expression analysis. This study describes the identification and characterization of …
expression analysis. This study describes the identification and characterization of …
[PDF][PDF] Identification of microRNA‐181 by genome‐wide screening as a critical player in EpCAM–positive hepatic cancer stem cells
J Ji, T Yamashita, A Budhu, M Forgues, HL Jia… - …, 2009 - Wiley Online Library
MicroRNAs (miRNAs) are endogenous small noncoding RNAs that regulate gene
expression with functional links to tumorigenesis. Hepatocellular carcinoma (HCC) is the …
expression with functional links to tumorigenesis. Hepatocellular carcinoma (HCC) is the …
miR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to “seedless” 3′ UTR microRNA recognition elements
Summary miR-24, upregulated during terminal differentiation of multiple lineages, inhibits
cell-cycle progression. Antagonizing miR-24 restores postmitotic cell proliferation and …
cell-cycle progression. Antagonizing miR-24 restores postmitotic cell proliferation and …
Micromanagement of the immune system by microRNAs
MicroRNAs (miRNAs) are an abundant class of evolutionarily conserved small non-coding
RNAs that are thought to control gene expression by targeting mRNAs for degradation or …
RNAs that are thought to control gene expression by targeting mRNAs for degradation or …
miR-22 represses cancer progression by inducing cellular senescence
D Xu, F Takeshita, Y Hino, S Fukunaga, Y Kudo… - Journal of Cell …, 2011 - rupress.org
Cellular senescence acts as a barrier to cancer progression, and microRNAs (miRNAs) are
thought to be potential senescence regulators. However, whether senescence-associated …
thought to be potential senescence regulators. However, whether senescence-associated …