Therapeutic potential of psychedelic drugs: navigating high hopes, strong claims, weak evidence, and big money

K Humphreys, P Todd Korthuis… - Annual Review of …, 2024 - annualreviews.org
Therapeutic claims about many psychedelic drugs have not been evaluated in any studies
of even modest rigor. The science of psychedelic drugs is strengthening however, making it …

Buprenorphine initiation strategies for opioid use disorder and pain management: a systematic review

LA Spreen, EN Dittmar, KC Quirk… - … : The Journal of Human …, 2022 - Wiley Online Library
Buprenorphine possesses many unique attributes that make it a practical agent for adults
and adolescents with opioid use disorder (OUD) and/or acute or chronic pain. Sublingual …

Opioid analgesia for acute low back pain and neck pain (the OPAL trial): a randomised placebo-controlled trial

CMP Jones, RO Day, BW Koes, J Latimer, CG Maher… - The Lancet, 2023 - thelancet.com
Background Opioid analgesics are commonly used for acute low back pain and neck pain,
but supporting efficacy data are scarce. We aimed to investigate the efficacy and safety of a …

Racial and ethnic disparities in drug overdose deaths in the US during the COVID-19 pandemic

B Han, EB Einstein, CM Jones, J Cotto… - JAMA network …, 2022 - jamanetwork.com
Recent reports highlighted racial and ethnic differences in US drug overdose deaths from
1999 to 2020. 1, 2 Overdose deaths increased 37.2% from February 2020 to August 2021 …

Modulation of 5-HT release by dynorphin mediates social deficits during opioid withdrawal

MB Pomrenze, DFC Pinto, PA Neumann, P Llorach… - Neuron, 2022 - cell.com
Social isolation during opioid withdrawal is a major contributor to the current opioid
addiction crisis. We find that sociability deficits during protracted opioid withdrawal in mice …

Reducing opioid use disorder and overdose deaths in the United States: a dynamic modeling analysis

EJ Stringfellow, TY Lim, K Humphreys… - Science …, 2022 - science.org
Opioid overdose deaths remain a major public health crisis. We used a system dynamics
simulation model of the US opioid-using population age 12 and older to explore the impacts …

Racial and ethnic disparities in opioid access and urine drug screening among older patients with poor-prognosis cancer near the end of life

AC Enzinger, K Ghosh, NL Keating… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE To characterize racial and ethnic disparities and trends in opioid access and
urine drug screening (UDS) among patients dying of cancer, and to explore potential …

Fentanyl-driven acceleration of racial, gender and geographical disparities in drug overdose deaths in the United States

MR D'Orsogna, L Böttcher, T Chou - PLOS Global Public Health, 2023 - journals.plos.org
We examine trends in drug overdose deaths by race, gender, and geography in the United
States during the period 2013–2020. Race and gender specific crude rates were extracted …

[BOK][B] The sociology of health, healing, and illness

G Weiss, D Copelton - 2023 - taylorfrancis.com
With thorough coverage of inequality in health care access and practice across the field it
surveys, The Sociology of Health, Healing, and Illness is widely acclaimed by instructors as …

Effectiveness of policies for addressing the US opioid epidemic: a model-based analysis from the Stanford-Lancet Commission on the North American Opioid Crisis

IJ Rao, K Humphreys, ML Brandeau - The Lancet Regional Health …, 2021 - thelancet.com
Introduction The US opioid crisis has been exacerbated by COVID-19 and the spread of
synthetic opioids (eg, fentanyl). Methods We model the effectiveness of reduced prescribing …