Osteoporosis and periodontal diseases–An update on their association and mechanistic links
Periodontitis and osteoporosis are prevalent inflammation‐associated skeletal disorders that
pose significant public health challenges to our aging population. Both periodontitis and …
pose significant public health challenges to our aging population. Both periodontitis and …
Birth and death of bone cells: basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis
SC Manolagas - Endocrine reviews, 2000 - academic.oup.com
The adult skeleton regenerates by temporary cellular structures that comprise teams of
juxtaposed osteoclasts and osteoblasts and replace periodically old bone with new. A …
juxtaposed osteoclasts and osteoblasts and replace periodically old bone with new. A …
Therapeutic approaches to bone diseases
GA Rodan, TJ Martin - Science, 2000 - science.org
The strength and integrity of our bones depends on maintaining a delicate balance between
bone resorption by osteoclasts and bone formation by osteoblasts. As we age or as a result …
bone resorption by osteoclasts and bone formation by osteoblasts. As we age or as a result …
[BOOK][B] Bone mechanics handbook
SC Cowin - 2001 - taylorfrancis.com
This second edition of the Bone Mechanics Handbook summarizes the current
understanding of bone mechanics with comprehensive coverage of the histology …
understanding of bone mechanics with comprehensive coverage of the histology …
Physiological bone remodeling: systemic regulation and growth factor involvement
Bone remodeling is essential for adult bone homeostasis. It comprises two phases: bone
formation and resorption. The balance between the two phases is crucial for sustaining bone …
formation and resorption. The balance between the two phases is crucial for sustaining bone …
Glucocorticoid-induced osteoporosis: an update
J Compston - Endocrine, 2018 - Springer
Glucocorticoid-induced osteoporosis is the most common secondary cause of osteoporosis
and the resulting fractures cause significant morbidity. Following initiation of oral …
and the resulting fractures cause significant morbidity. Following initiation of oral …
Staphylococcal osteomyelitis: disease progression, treatment challenges, and future directions
N Kavanagh, EJ Ryan, A Widaa, G Sexton… - Clinical microbiology …, 2018 - Am Soc Microbiol
Osteomyelitis is an inflammatory bone disease that is caused by an infecting microorganism
and leads to progressive bone destruction and loss. The most common causative species …
and leads to progressive bone destruction and loss. The most common causative species …
Glucocorticoid-induced osteoporosis: pathophysiology and therapy
Glucocorticoid-induced osteoporosis (GIO) is the most common form of secondary
osteoporosis. Fractures, which are often asymptomatic, may occur in as many as 30–50% of …
osteoporosis. Fractures, which are often asymptomatic, may occur in as many as 30–50% of …
Nongenotropic, sex-nonspecific signaling through the estrogen or androgen receptors: dissociation from transcriptional activity
The relationship of the classical receptors and their transcriptional activity to nongenotropic
effects of steroid hormones is unknown. We demonstrate herein a novel paradigm of sex …
effects of steroid hormones is unknown. We demonstrate herein a novel paradigm of sex …
The effects of parathyroid hormone and alendronate alone or in combination in postmenopausal osteoporosis
Background Parathyroid hormone increases bone strength primarily by stimulating bone
formation, whereas antiresorptive drugs reduce bone resorption. We conducted a …
formation, whereas antiresorptive drugs reduce bone resorption. We conducted a …