Conventional chemotherapy, one of the most widely used cancer treatment methods, has
serious side effects, and usually results in cancer treatment failure. Drug resistance is one of …

Immunotherapy based on immune checkpoint inhibitors has evolved into a new pillar of
cancer treatment in clinics, but dealing with treatment resistance (either primary or acquired) …

The flow of interstitial fluid and the associated interstitial fluid pressure (IFP) in solid tumors
and surrounding host tissues have been identified as critical elements in cancer growth and …

Local implantable drug delivery system (IDDS) can be used as an effective adjunctive
therapy for solid tumor following thermal ablation for destroying the residual cancer cells and …

Highlights•Systems biology approaches support drug development efforts.•Models of
angiogenesis aid in testing anti-angiogenic therapeutic strategies.•Models provide novel …

Tumor interstitial fluid pressure (TIFP), is a physiological parameter with demonstrated
predictive value for a tumor's aggressiveness, drug delivery, as well as response to …

Nanomedicine for cancer, where nanoparticles (NPs) are used to deliver drugs, imaging
agents, and heat to tumors, shows great potential of improved therapeutic outcomes. In spite …

Angiogenesis is the growth of new capillaries from preexisting ones. The ability to trigger
angiogenesis is one of the hallmarks of cancer, and is a necessary step for a tumor to …

Convection-enhanced delivery of rhenium-186 (186 Re)-nanoliposomes is a promising
approach to provide precise delivery of large localized doses of radiation for patients with …

Myocarditis is a general set of mechanisms that manifest themselves into the inflammation of
the heart muscle. In 2017, more than 3 million people were affected by this disease …