Application of cyclodextrins in chiral capillary electrophoresis

P Řezanka, K Navrátilová, M Řezanka, V Král… - …, 2014 - Wiley Online Library
CE represents a very powerful separation tool in the area of chiral separations. CD‐
mediated chiral CE is a continuously flourishing technique within the frame of the …

Recent advances in electrodriven enantioseparations

P Jáč, GKE Scriba - Journal of separation science, 2013 - Wiley Online Library
Capillary electromigration techniques have developed into significant analytical separation
tools especially for enantioseparations. While CE can be considered a mature technique as …

Facile and sensitive determination of N-nitrosamines in food samples by high-performance liquid chromatography via combining fluorescent labeling with dispersive …

S Lu, D Wu, G Li, Z Lv, P Gong, L **a, Z Sun, G Chen… - Food chemistry, 2017 - Elsevier
The intake of N-nitrosamines (NAs) from foodstuffs is considered to be an important
influence factor for several cancers. But the rapid and sensitive screening of NAs remains a …

Carcinogenicity and DNA adduct formation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1 …

S Balbo, CS Johnson, RC Kovi, SA James-Yi… - …, 2014 - academic.oup.com
(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) is metabolized to enantiomers of 4-
(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), found in the urine of virtually all people …

A comprehensive methodology for the chiral separation of 40 tobacco alkaloids and their carcinogenic E/Z-(R, S)-tobacco-specific nitrosamine metabolites

G Hellinghausen, D Roy, Y Wang, JT Lee, DA Lopez… - Talanta, 2018 - Elsevier
The predominant enantiomer of nicotine found in nature is (S)-nicotine and its pharmacology
has been widely established. However, pharmacologic information concerning individual …

A chemometric experimental design with three-step stacking capillary electrophoresis for analysis of five tobacco-specific nitrosamines in cigarette products

CW Cheng, HS Kou, SM Wu, CC Wang - Journal of Chromatography A, 2022 - Elsevier
Tobacco-specific nitrosamines (TSNAs) as carcinogens endanger our health and life from
cigarette products. However, the safe range of TSNAs levels in commercial cigarette …

Bioanalysis of drugs and their metabolites by chiral electromigration techniques (2010–2020)

J Caslavska, W Thormann - Electrophoresis, 2021 - Wiley Online Library
The further development and application of capillary electromigration techniques for the
enantioselective determination of drugs and their metabolites in body fluids, tissues, and in …

New approaches in sensitive chiral CE

L Sánchez‐Hernández, M Guijarro‐Diez… - …, 2014 - Wiley Online Library
CE has shown to have a big potential for chiral separations, with advantages such as high
efficiency, high resolution, and low sample and reagents consumption. Nevertheless, when …

Enantiomeric separation of five acidic drugs via capillary electrophoresis using streptomycin as chiral selector

X Zhang, S Qi, C Liu, X Zhao - Journal of Chromatography B, 2017 - Elsevier
A simple capillary zone electrophoresis (CZE) method was developed to achieve the rapid
enantiomeric separation of a set of acidic drugs using streptomycin as chiral selector. The …

Normal phase LC coupled with direct analysis in real time MS for the chiral analysis of 4‐(methylnitrosamino)‐1‐(3‐pyridyl)‐1‐butanol and jasmonic acid

C Chang, Z Zhou, Y Yang, Y Han, Y Bai… - …, 2012 - Wiley Online Library
Normal phase chiral LC (NPLC) has been proved to be powerful and efficient for chiral
separation. However, the combination of NPLC with ESI or atmospheric pressure chemical …