Dysfunctional glucose metabolism in Alzheimer's disease onset and potential pharmacological interventions
Alzheimer's disease (AD) is the most common age-related dementia. The alteration in
metabolic characteristics determines the prognosis. Patients at risk show reduced glucose …
metabolic characteristics determines the prognosis. Patients at risk show reduced glucose …
Ultra-high-field MRI in the diagnosis and management of gliomas: a systematic review
Importance: Gliomas, tumors of the central nervous system, are classically diagnosed
through invasive surgical biopsy and subsequent histopathological study. Innovations in …
through invasive surgical biopsy and subsequent histopathological study. Innovations in …
Altered d-glucose in brain parenchyma and cerebrospinal fluid of early Alzheimer's disease detected by dynamic glucose-enhanced MRI
Altered cerebral glucose uptake is one of the hallmarks of Alzheimer's disease (AD). A
dynamic glucose-enhanced (DGE) magnetic resonance imaging (MRI) approach was …
dynamic glucose-enhanced (DGE) magnetic resonance imaging (MRI) approach was …
d‐glucose weighted chemical exchange saturation transfer (glucoCEST)‐based dynamic glucose enhanced (DGE) MRI at 3T: early experience in healthy volunteers …
Purpose Dynamic glucose enhanced (DGE) MRI has shown potential for imaging glucose
delivery and blood–brain barrier permeability at fields of 7T and higher. Here, we evaluated …
delivery and blood–brain barrier permeability at fields of 7T and higher. Here, we evaluated …
Imaging of sugar‐based contrast agents using their hydroxyl proton exchange properties
The ability of CEST MRI to detect the presence of millimolar concentrations of non‐metallic
contrast agents has made it possible to study, non‐invasively, important biological …
contrast agents has made it possible to study, non‐invasively, important biological …
Molecular imaging of brain tumors and drug delivery using CEST MRI: promises and challenges
Chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) detects
molecules in their natural forms in a sensitive and non-invasive manner. This makes it a …
molecules in their natural forms in a sensitive and non-invasive manner. This makes it a …
Preclinical applications of multi-platform imaging in animal models of cancer
In animal models of cancer, oncologic imaging has evolved from a simple assessment of
tumor location and size to sophisticated multimodality exploration of molecular, physiologic …
tumor location and size to sophisticated multimodality exploration of molecular, physiologic …
Metabolic brain imaging with glucosamine CEST MRI: in vivo characterization and first insights
The utility of chemical exchange saturation transfer (CEST) MRI for monitoring the uptake of
glucosamine (GlcN), a safe dietary supplement, has been previously demonstrated in …
glucosamine (GlcN), a safe dietary supplement, has been previously demonstrated in …
Repurposing clinical agents for chemical exchange saturation transfer magnetic resonance imaging: current status and future perspectives
Molecular imaging is becoming an indispensable tool to pursue precision medicine.
However, quickly translating newly developed magnetic resonance imaging (MRI) agents …
However, quickly translating newly developed magnetic resonance imaging (MRI) agents …
Radiofrequency labeling strategies in chemical exchange saturation transfer MRI
Chemical exchange saturation transfer (CEST) MRI has generated great interest for
molecular imaging applications because it can image low‐concentration solute molecules in …
molecular imaging applications because it can image low‐concentration solute molecules in …