Zinc coordination complexes as anticancer agents

M Pellei, F Del Bello, M Porchia, C Santini - Coordination Chemistry …, 2021 - Elsevier
Zinc, present in all forms of life, is an essential element for humans. It is one of the most
abundant metals in our body. Because of its importance, any malfunctions of its homeostasis …

Studying non-covalent drug–DNA interactions

SU Rehman, T Sarwar, MA Husain, HM Ishqi… - Archives of biochemistry …, 2015 - Elsevier
Drug–DNA interactions have been extensively studied in the recent past. Various
techniques have been employed to decipher these interactions. DNA is a major target for a …

Copper (II) and zinc (II) coordination compounds of non-steroidal anti-inflammatory drugs: Structural features and antioxidant activity

G Psomas - Coordination Chemistry Reviews, 2020 - Elsevier
Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used analgesic, anti-
inflammatory and antipyretic agents with known side-effects. The most important NSAIDs are …

Zinc complexes with nitrogen donor ligands as anticancer agents

M Porchia, M Pellei, F Del Bello, C Santini - Molecules, 2020 - mdpi.com
The search for anticancer metal-based drugs alternative to platinum derivatives could not
exclude zinc derivatives due to the importance of this metal for the correct functioning of the …

Bovine serum albumin interactions with metal complexes

T Topală, A Bodoki, L Oprean, R Oprean - Clujul medical, 2014 - pmc.ncbi.nlm.nih.gov
The continuous search for new molecules with therapeutic abilities has led to the synthesis
and characterization of a large number of metal complexes, proven to exhibit potential as …

Anti-cancer property and DNA binding interaction of first row transition metal complexes: a decade update

U Dasmahapatra, B Maiti, MM Alam… - European Journal of …, 2024 - Elsevier
Metal ions carry out a wide variety of functions, including acid-base/redox catalysis,
structural functions, signaling, and electron transport. Understanding the interactions of …

Non‐steroidal anti‐inflammatory drugs (NSAIDs) in metal complexes and their effect at the cellular level

CN Banti, SK Hadjikakou - European Journal of Inorganic …, 2016 - Wiley Online Library
The nonsteroidal anti‐inflammatory drugs (NSAIDs) make up a great group of drugs that
provide benefits in the prevention of cancers. Coordinated metal ions with NSAIDs provide …

NSAID-based coordination compounds for biomedical applications: recent advances and developments

ACF Santos, LPG Monteiro, ACC Gomes… - International journal of …, 2022 - mdpi.com
After the serendipitous discovery of cisplatin, a platinum-based drug with chemotherapeutic
effects, an incredible amount of research in the area of coordination chemistry has been …

Synthesis and anticancer mechanisms of zinc (II)-8-hydroxyquinoline complexes with 1, 10-phenanthroline ancillary ligands

LQ Du, TY Zhang, XM Huang, Y Xu, MX Tan… - Dalton …, 2023 - pubs.rsc.org
Twenty new zinc (II) complexes with 8-hydroxyquinoline (H-Q1–H-Q6) in the presence of 1,
10-phenanthroline derivatives (D1–D10) were synthesized and formulated as [Zn (Q1) 2 …

Synthesis, structure and biological activity of nickel (II) complexes with mefenamato and nitrogen-donor ligands

X Totta, AA Papadopoulou, AG Hatzidimitriou… - Journal of inorganic …, 2015 - Elsevier
Six novel nickel (II) complexes with the non-steroidal anti-inflammatory drug mefenamic acid
(Hmef) with the nitrogen-donor heterocyclic ligands 2, 2′-bipyridine (bipy), 2, 2 …