One hundred years have passed since Warburg discovered alterations in cancer
metabolism, more than 70 years since Sidney Farber introduced anti-folates that …

As knowledge of cell metabolism has advanced, glutamine has been considered an
important amino acid that supplies carbon and nitrogen to fuel biosynthesis. A recent study …

Cancer cells characteristically consume glucose through Warburg metabolism, a process
that forms the basis of tumour imaging by positron emission tomography (PET). Tumour …

Proliferating cancer cells rely largely on glutamine for survival and proliferation. Glutamine
serves as a carbon source for the synthesis of lipids and metabolites via the TCA cycle, as …

Oncogenic signalling and metabolic alterations are interrelated in cancer cells. mTOR,
which is frequently activated in cancer, controls cell growth and metabolism. mTOR …

Hepatocellular carcinoma (HCC) is an aggressive human cancer with increasing incidence
worldwide. Multiple efforts have been made to explore pharmaceutical therapies to treat …

Abstract Over 90 years ago, Otto Warburg's seminal discovery of aerobic glycolysis
established metabolic reprogramming as one of the first distinguishing characteristics of …

Aberrant metabolism is a major hallmark of cancer. Abnormal cancer metabolism, such as
aerobic glycolysis and increased anabolic pathways, has important roles in tumorigenesis …

Amino acids are fundamental building blocks supporting life. Their role in protein synthesis
is well defined, but they contribute to a host of other intracellular metabolic pathways …

Phototheranostics has received sustained attention due to its great potential in
revolutionizing conventional strategies of cancer treatment. However, trapped by the …