The tumor necrosis factor (TNF) and TNF receptor (TNFR) superfamilies (TNFSF/TNFRSF)
include 19 ligands and 29 receptors that play important roles in the modulation of cellular …

The tumor necrosis factor (TNF) cytokine family and the TNF/nerve growth factor (NGF)
family of their cognate receptors together control numerous immune functions, as well as …

Earlier studies on elucidating the role of lymphocytes in tumor immunity predominantly
focused on T cells. However, the role of B cells in tumor immunity has increasingly received …

Tertiary lymphoid structures (TLSs) are associated with anti-tumor response following
immune checkpoint inhibitor (ICI) therapy, but a commensurate observation of TLS is absent …

Background Patients with inflammatory bowel disease (IBD) and healthy controls received
primary SARS-CoV-2-mRNA vaccination and a booster after six months. Anti-TNF-α-treated …

Growing evidences put B lymphocytes on a central stage in multiple sclerosis (MS)
immunopathology. While investigating the effects of interferon‐β (IFN‐β) therapy, one of the …

Background Fine particulate matter (PM2. 5) is a crucial risk factor for chronic obstructive
pulmonary disease (COPD). However, the mechanisms whereby PM2. 5 contribute to COPD …

Most ligands and receptors from the tumor necrosis factor (TNF) superfamily play very
important roles in the immune system. In particular, many of these molecules are essential in …

TNF–α influences lymphomagenesis by upregulating proinflammatory and antiapoptotic
pathways. In this study, we evaluated the frequency of TNF–α rs1800629 (–308 G> A) …

Objective Fas/Fas ligand (FasL) and B cell-activating factor (BAFF) signalling have pivotal
roles in SLE pathogenesis. We investigated the clinical associations of serum …