Abstract 293 cell line (widely known as the Human Embryonic Kidney 293 cells) and its
derivatives were the most used cells after HeLa in cell biology studies and after CHO in …

Globally, the central nervous system (CNS) disorders appear as the most critical
pathological threat with no proper cure. Alzheimer's disease (AD) is one such condition …

Summary Human myxovirus resistance 2 (MX2) can restrict HIV-1 and herpesviruses at a
post-entry step through a process requiring an interaction between MX2 and the viral …

Packaging or producer cell lines for scalable recombinant adeno-associated virus (rAAV)
production have been notoriously difficult to create due in part to the cytostatic nature of the …

Wnt signaling orchestrates gene expression via its effector, β-catenin. However, it is
unknown whether β-catenin binds its target genomic regions simultaneously and how this …

Human exposures to perfluoroalkyl and polyfluoroalkyl substances (PFAS) have been linked
to several diseases associated with adverse health outcomes. Animal studies have been …

Sialic acids (Sia) are widely displayed on the surfaces of cells and tissues. Sia come in a
variety of chemically modified forms, including those with acetyl modifications at the C-7, C …

Measles virus (MeV), an enveloped RNA virus in the family Paramyxoviridae, is still an
important cause of childhood morbidity and mortality worldwide. MeV usually causes acute …

Mutations in the human INF2 gene cause autosomal dominant focal segmental
glomerulosclerosis (FSGS)—a condition characterized by podocyte loss, scarring, and …

After axonal insult and injury, Dual leucine-zipper kinase (DLK) conveys retrograde pro-
degenerative signals to neuronal cell bodies via its downstream target c-Jun N-terminal …