Where is nano today and where is it headed? A review of nanomedicine and the dilemma of nanotoxicology

C Domingues, A Santos, C Alvarez-Lorenzo… - ACS …, 2022 - ACS Publications
Worldwide nanotechnology development and application have fueled many scientific
advances, but technophilic expectations and technophobic demands must be …

Polymeric nanoparticles-loaded hydrogels for biomedical applications: a systematic review on in vivo findings

D Nunes, S Andrade, MJ Ramalho, JA Loureiro… - Polymers, 2022 - mdpi.com
Clinically available medications face several hurdles that limit their therapeutic activity,
including restricted access to the target tissues due to biological barriers, low bioavailability …

Delivery of CAR-T cells in a transient injectable stimulatory hydrogel niche improves treatment of solid tumors

AK Grosskopf, L Labanieh, DD Klysz, GA Roth, P Xu… - Science …, 2022 - science.org
Adoptive cell therapy (ACT) has proven to be highly effective in treating blood cancers, but
traditional approaches to ACT are poorly effective in treating solid tumors observed …

Supramolecular reinforcement of polymer–nanoparticle hydrogels for modular materials design

G Bovone, EA Guzzi, S Bernhard, T Weber… - Advanced …, 2022 - Wiley Online Library
Moldable hydrogels are increasingly used as injectable or extrudable materials in
biomedical and industrial applications owing to their ability to flow under applied stress …

Hydrogels in dental medicine

W Chen, C Zhang, S Peng, Y Lin… - Advanced Therapeutics, 2024 - Wiley Online Library
Oral diseases are a prevalent global health problem that are primarily characterized by
microbial infections, inflammation, and destruction of oral tissues. Maintaining good oral …

Use of a biomimetic hydrogel depot technology for sustained delivery of GLP-1 receptor agonists reduces burden of diabetes management

AI d'Aquino, CL Maikawa, LT Nguyen, K Lu, IA Hall… - Cell Reports …, 2023 - cell.com
Summary Glucagon-like peptide-1 (GLP-1) is an incretin hormone and neurotransmitter
secreted from intestinal L cells in response to nutrients to stimulate insulin and block …

[HTML][HTML] Injectable liposome-based supramolecular hydrogels for the programmable release of multiple protein drugs

S Correa, AK Grosskopf, JH Klich, HL Hernandez… - Matter, 2022 - cell.com
Directing biological functions is at the heart of next-generation biomedical initiatives in tissue
and immuno-engineering. However, the ambitious goal of engineering complex biological …

Gelation and yielding behavior of polymer–nanoparticle hydrogels

AK Grosskopf, OA Saouaf… - Journal of Polymer …, 2021 - Wiley Online Library
Polymer–nanoparticle hydrogels are a unique class of self‐assembled, shear‐thinning, yield‐
stress fluids that have demonstrated potential utility in many impactful applications. Here, we …

Self-healing Au/PVDF-HFP composite ionic gel for flexible underwater pressure sensor

R Yin, L Li, L Wang, Z Lou - Journal of Semiconductors, 2023 - iopscience.iop.org
Ionic gels can be potentially used in wearable devices owing to their high humidity
resistance and non-volatility. However, the applicability of existing ionic gel pressure …

Advances in cancer diagnosis and therapy by alginate-based multifunctional hydrogels: A review

Z Wang, X Han, G Sun, M Yu, J Qin, Y Zhang… - International Journal of …, 2024 - Elsevier
The field of oncology has been changed by the application of hydrogels. These 3D
polymeric networks have demonstrated significant promise in the treatment of cancer and …