The metabolite 2-oxoglutarate (also known as α-ketoglutarate, 2-ketoglutaric acid, or
oxoglutaric acid) lies at the intersection between the carbon and nitrogen metabolic …

A wide range of Bacteria and Archaea sense cellular 2-oxoglutarate (2OG) as an indicator of
nitrogen limitation. 2OG sensor proteins are varied, but most of those studied belong to the …

Microbially mediated nitrogen cycling in carbon-dominated cold seep environments remains
poorly understood. So far anaerobic methanotrophic archaea (ANME-2) and their sulfate …

The tree of life is split into three main branches: eukaryotes, bacteria, and archaea. Our
knowledge of eukaryotic and bacteria cell biology has been built on a foundation of studies …

The PII proteins are one of the most widely distributed families of signal transduction
proteins in nature. They are pivotal players in the control of nitrogen metabolism in bacteria …

The metabolism of carbon-and nitrogen-containing compounds is fundamental to all forms of
life. To cope with changing environmental conditions, bacteria have to sense the nutrient …

Molybdenum nitrogenase (Nif), which catalyzes the reduction of dinitrogen to ammonium,
has modulated the availability of fixed nitrogen in the biosphere since early in Earth's history …

Despite decades of study, electron flow and energy conservation in methanogenic Archaea
are still not thoroughly understood. For methanogens without cytochromes, flavin-based …

The Amt/Mep/Rh family of integral membrane proteins comprises ammonium transporters of
bacteria, archaea and eukarya, as well as the Rhesus proteins found in animals. They play a …

Methanococcus maripaludis is a rapidly growing, fully sequenced, genetically tractable
model organism among hydrogenotrophic methanogens. It has the ability to convert CO 2 …