Radiochemistry for positron emission tomography

J Rong, A Haider, TE Jeppesen, L Josephson… - Nature …, 2023 - nature.com
Positron emission tomography (PET) constitutes a functional imaging technique that is
harnessed to probe biological processes in vivo. PET imaging has been used to diagnose …

Radiopharmaceuticals for PET and SPECT imaging: a literature review over the last decade

G Crișan, NS Moldovean-Cioroianu… - International journal of …, 2022 - mdpi.com
Positron emission tomography (PET) uses radioactive tracers and enables the functional
imaging of several metabolic processes, blood flow measurements, regional chemical …

Modern transition-metal-catalyzed carbon–halogen bond formation

DA Petrone, J Ye, M Lautens - Chemical Reviews, 2016 - ACS Publications
The high utility of halogenated organic compounds has prompted the development of a vast
number of transformations which install the carbon–halogen motif. Traditional routes to …

18F-Labeling of Arenes and Heteroarenes for Applications in Positron Emission Tomography

S Preshlock, M Tredwell, V Gouverneur - Chemical reviews, 2016 - ACS Publications
Diverse radiochemistry is an essential component of nuclear medicine; this includes
imaging techniques such as positron emission tomography (PET). As such, PET can track …

Chemistry for Positron Emission Tomography: Recent Advances in 11C‐, 18F‐, 13N‐, and 15O‐Labeling Reactions

X Deng, J Rong, L Wang, N Vasdev… - Angewandte Chemie …, 2019 - Wiley Online Library
Positron emission tomography (PET) is a molecular imaging technology that provides
quantitative information about function and metabolism in biological processes in vivo for …

18F-Fluorination: Challenge and Opportunity for Organic Chemists

R Halder, T Ritter - The Journal of Organic Chemistry, 2021 - ACS Publications
18F-fluorination is an important and growing field in organic synthesis that has attracted
many chemists in the recent past. Here we present our own, biased perspective with a focus …

Iridium‐catalysed C− H borylation of heteroarenes: balancing steric and electronic regiocontrol

JS Wright, PJH Scott, PG Steel - … Chemie International Edition, 2021 - Wiley Online Library
The iridium‐catalysed borylation of aromatic C− H bonds has become the preferred method
for the synthesis of aromatic organoboron compounds. The reaction is highly efficient …

Fluorine-18 labelled building blocks for PET tracer synthesis

D Van Der Born, A Pees, AJ Poot, RVA Orru… - Chemical Society …, 2017 - pubs.rsc.org
Positron emission tomography (PET) is an important driver for present day healthcare.
Fluorine-18 is the most widely used radioisotope for PET imaging and a thorough overview …

Derisking the Cu-Mediated 18F-Fluorination of Heterocyclic Positron Emission Tomography Radioligands

NJ Taylor, E Emer, S Preshlock… - Journal of the …, 2017 - ACS Publications
Molecules labeled with fluorine-18 (18F) are used in positron emission tomography to
visualize, characterize and measure biological processes in the body. Despite recent …